ZFIN is now using GRCz12tu for Genomic Data
Gene
krt4
- ID
- ZDB-GENE-000607-83
- Name
- keratin 4
- Symbol
- krt4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Is expressed in several structures, including digestive system; ectoderm; endocrine system; head; and integument. Human ortholog(s) of this gene implicated in several diseases, including Meesmann corneal dystrophy 2; autosomal dominant woolly hair; hypotrichosis (multiple); ichthyosis (multiple); and palmoplantar keratosis (multiple). Orthologous to several human genes including KRT8 (keratin 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 50 figures from 29 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb59 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Intermediate filament, rod domain | Keratin, type II | Keratin type II head |
|---|---|---|---|---|---|
| UniProtKB:F1QK60 | InterPro | 497 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers