ZFIN is now using GRCz12tu for Genomic Data
Gene
copz1
- ID
- ZDB-GENE-000406-6
- Name
- coat protein complex I subunit zeta 1
- Symbol
- copz1 Nomenclature History
- Previous Names
-
- CHUNP6876
- zeta1-cop
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within lens development in camera-type eye. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Orthologous to human COPZ1 (coat protein complex I subunit zeta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66334 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neutropenia, severe congenital, 12, autosomal recessive | 621439 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AP complex, mu/sigma subunit | Clathrin adaptor complex, small chain | Coatomer subunit zeta | Longin-like domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q9IB48 | InterPro | 177 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers