Gene
ccnb1
- ID
- ZDB-GENE-000406-10
- Name
- cyclin B1
- Symbol
- ccnb1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Is predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in mitotic cell cycle phase transition; mitotic metaphase plate congression; and regulation of cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within oocyte maturation. Predicted to colocalize with mitochondrial matrix. Is expressed in several structures, including nervous system; oocyte; pectoral fin; trunk mesenchyme; and unfertilized egg. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 58 figures from 32 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb267 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclin | Cyclin, C-terminal domain | Cyclin-like | Cyclin-like superfamily | Cyclin, N-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:O42092
|
264 | |||||
|
UniProtKB:F8W257
|
219 | |||||
|
UniProtKB:Q7ZU21
|
397 | |||||
|
UniProtKB:F8W534
|
71 | |||||
|
UniProtKB:Q9IB44
|
398 | |||||
|
UniProtKB:F8W498
|
85 |
Interactions and Pathways
No data available
Plasmids
No data available