Gene
meis2b
- ID
- ZDB-GENE-000210-23
- Name
- Meis homeobox 2b
- Symbol
- meis2b Nomenclature History
- Previous Names
-
- meis2.1
- meis2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Is predicted to enable DNA binding activity. Acts upstream of or within cardiac atrium morphogenesis and heart looping. Predicted to be located in nucleus. Is expressed in several structures, including anterior neural keel; heart rudiment; nervous system; neural plate; and pericardial region. Human ortholog(s) of this gene implicated in cleft palate, cardiac defects, and intellectual disabillity. Orthologous to human MEIS2 (Meis homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76815 (20 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cleft palate, cardiac defects, and intellectual disabillity | Alliance | Cleft palate, cardiac defects, and mental retardation | 600987 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox domain | Homeobox KN domain | Homeobox-like domain superfamily | Homeobox protein PKNOX/Meis, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q9DDE0
|
|||||
|
UniProtKB:Q9PTM7
|
393 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
meis2b-203
(1)
|
3104 nt | |
| ncRNA |
meis2b-002
(1)
|
843 nt |
Interactions and Pathways
No data available
Plasmids
No data available