ZFIN ID: ZDB-FISH-220728-15
Fish name: plpbpot101/+; plpbpot102/+
Genotype: plpbpot101/+; plpbpot102/+
Targeting Reagent: none
HUMAN DISEASE MODELED by plpbpot101/+; plpbpot102/+
Human Disease Conditions Citations
early-onset vitamin B6-dependent epilepsy standard conditions Johnstone et al., 2019
GENE EXPRESSION
Gene expression in plpbpot101/+; plpbpot102/+
RNA expression
Expressed Gene Structure Conditions Figures
fosab standard conditions Fig. 4 from Johnstone et al., 2019
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in plpbpot101/+; plpbpot102/+
Phenotype Conditions Figures
brain synaptic signaling ictal, abnormal standard conditions Fig. 4 from Johnstone et al., 2019
optic tectum synaptic signaling ictal, ameliorated chemical treatment by environment: pyridoxine Fig. 5 from Johnstone et al., 2019
whole organism dead, abnormal standard conditions Fig. 4 from Johnstone et al., 2019
whole organism dead, ameliorated chemical treatment by environment: pyridoxine Fig. 5 from Johnstone et al., 2019
whole organism dead, ameliorated chemical treatment by environment: pyridoxal 5'-phosphate Fig. 5 from Johnstone et al., 2019
whole organism decreased life span, abnormal standard conditions Fig. 4 from Johnstone et al., 2019
whole organism decreased life span, ameliorated chemical treatment by environment: pyridoxine Fig. 5 from Johnstone et al., 2019
whole organism decreased life span, ameliorated chemical treatment by environment: pyridoxal 5'-phosphate Fig. 5 from Johnstone et al., 2019
whole organism fosab expression increased amount, abnormal standard conditions Fig. 4 from Johnstone et al., 2019
whole organism 3-aminoisobutyric acid increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism alanine decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism alpha-aminobutyric acid decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism asparagine decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism beta-alanine increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism cystathionine increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism gamma-aminobutyric acid decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism glutamine decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism isoleucine increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism lysine decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism methionine increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism phenylalanine increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism proline decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism pyridoxal decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism pyridoxal 5'-phosphate decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism swimming behavior increased process quality, abnormal standard conditions Fig. 4 from Johnstone et al., 2019
whole organism swimming behavior increased process quality, ameliorated chemical treatment by environment: pyridoxine Fig. 5 from Johnstone et al., 2019
whole organism threonine decreased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism tryptophan increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019
whole organism tyrosine increased amount, abnormal standard conditions Fig. 6 from Johnstone et al., 2019

CITATIONS  (1)