ZFIN Fish: smyhc1^stl582/stl582

ZFIN ID: ZDB-FISH-220603-2

ZFIN ID: ZDB-FISH-220603-2

Fish name:	smyhc1^{stl582/stl582}
Genotype:	smyhc1^{stl582/stl582}
Targeting Reagent:	none

HUMAN DISEASE MODELED by smyhc1^{stl582/stl582}

Human Disease	Conditions	Citations
spondylocarpotarsal synostosis syndrome	standard conditions	Whittle et al., 2020

GENE EXPRESSION
Gene expression in smyhc1^{stl582/stl582}

RNA expression No data available

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab-F59		(not) muscle cell (not) whole organism	standard conditions	Figure 1 from Whittle et al., 2020
Ab1-actn		(not) slow muscle cell Z disc	standard conditions	Figure 6 from Whittle et al., 2020

Reporter gene expression No data available

PHENOTYPE
Phenotype in smyhc1^{stl582/stl582}

Phenotype	Conditions	Figures
motor behavior decreased process quality, abnormal	standard conditions	Figure 5 from Whittle et al., 2020
motor behavior normal process quality, normal	standard conditions	Figure 5 from Whittle et al., 2020
muscle cell ab-f59 labeling absent, abnormal	standard conditions	Figure 1 from Whittle et al., 2020
myotome normal length, normal	standard conditions	Figure 6 from Whittle et al., 2020
post-vent region curved dorsal, abnormal	standard conditions	Figure 4 from Whittle et al., 2020
post-vent region kinked, abnormal	standard conditions	Figure 4 from Whittle et al., 2020
slow muscle cell disorganized, abnormal	standard conditions	Figure 6 from Whittle et al., 2020
slow muscle cell shape, abnormal	standard conditions	Figure 6 from Whittle et al., 2020
slow muscle cell actin filament punctate, abnormal	standard conditions	Figure 6 from Whittle et al., 2020
slow muscle cell Z disc absent, abnormal	standard conditions	Figure 6 from Whittle et al., 2020
slow muscle cell Z disc ab1-actn labeling absent, abnormal	standard conditions	Figure 6 from Whittle et al., 2020
slow muscle cell Z disc ab1-actn labeling spatial pattern, abnormal	standard conditions	Figure 6 from Whittle et al., 2020
somite normal length, normal	standard conditions	Figure 6 from Whittle et al., 2020
trunk kinked, abnormal	standard conditions	Figure 4 from Whittle et al., 2020
vertebral column kinked, abnormal	standard conditions	Figure 4 from Whittle et al., 2020
whole organism ab-f59 labeling absent, abnormal	standard conditions	Figure 1 from Whittle et al., 2020
whole organism dead, abnormal	standard conditions	Figure 3 from Whittle et al., 2020
whole organism decreased life span, abnormal	standard conditions	Figure 3 from Whittle et al., 2020
whole organism morphology, normal	standard conditions	Figure 2 from Whittle et al., 2020
whole organism paralysed, abnormal	standard conditions	Figure 2 from Whittle et al., 2020

CITATIONS (1)