ZFIN Fish: nkgsaizGFFD1105AGt; zf2166Tg

ZFIN ID: ZDB-FISH-200130-11

ZFIN ID: ZDB-FISH-200130-11

Fish name:	nkgsaizGFFD1105AGt; zf2166Tg
Genotype:	nkgsaizGFFD1105AGt; zf2166Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by nkgsaizGFFD1105AGt; zf2166Tg

Human Disease	Conditions	Citations
intestinal cancer	control	Enya et al., 2018

GENE EXPRESSION
Gene expression in nkgsaizGFFD1105AGt; zf2166Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
cyp7a1	liver	control	Fig. 6 from Enya et al., 2018
eif4ebp1	whole organism	control	Fig. 5 from Enya et al., 2018
fgf21	intestine neoplasm	control	Fig. 6 from Enya et al., 2018
igfbp1a	intestine	control	Fig. 6 from Enya et al., 2018
il1b	intestine	control	Fig. 6 from Enya et al., 2018
il22	intestine neoplasm	control	Fig. 6 from Enya et al., 2018
insl5a	intestine neoplasm	control	Fig. 6 from Enya et al., 2018
lepb	intestine	control	Fig. 6 from Enya et al., 2018
mmp9	intestine	control	Fig. 3 from Enya et al., 2018
mmp13a	intestine	control	Fig. 3 from Enya et al., 2018
mmp14b	intestine	control	Fig. 3 from Enya et al., 2018

Protein expression No data available

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
EGFP	posterior intestine	control	Fig. 1 , Fig. 3 from Enya et al., 2018

PHENOTYPE
Phenotype in nkgsaizGFFD1105AGt; zf2166Tg

Phenotype	Conditions	Figures
growth decreased efficacy, abnormal	control	Fig. 5 from Enya et al., 2018
intestinal epithelium neoplastic, abnormal	control	Fig. 3 from Enya et al., 2018
intestine lepb expression increased amount, abnormal	control	Fig. 6 from Enya et al., 2018
intestine fgf21 expression increased amount, abnormal	control	Fig. 6 from Enya et al., 2018
intestine il1b expression increased amount, abnormal	control	Fig. 6 from Enya et al., 2018
intestine mmp14b expression increased amount, abnormal	control	Fig. 3 from Enya et al., 2018
intestine mmp9 expression increased amount, abnormal	control	Fig. 3 from Enya et al., 2018
intestine igfbp1a expression increased amount, abnormal	control	Fig. 6 from Enya et al., 2018
intestine il22 expression increased amount, abnormal	control	Fig. 6 from Enya et al., 2018
intestine mmp13a expression increased amount, abnormal	control	Fig. 3 from Enya et al., 2018
intestine insl5a expression increased amount, abnormal	control	Fig. 6 from Enya et al., 2018
intestine neoplastic, abnormal	control	Fig. 2 , Fig. 6 from Enya et al., 2018
intestine cell increased amount, abnormal	control	Fig. 2 from Enya et al., 2018
intestine cell population proliferation increased occurrence, abnormal	control	Fig. 2 from Enya et al., 2018
intestine neoplasm increased amount, abnormal	control	Fig. 2 from Enya et al., 2018
liver cyp7a1 expression decreased amount, abnormal	control	Fig. 6 from Enya et al., 2018
posterior intestine increased size, abnormal	control	Fig. 1 from Enya et al., 2018
whole organism decreased length, abnormal	control	Fig. 5 from Enya et al., 2018
whole organism decreased life span, abnormal	control	Fig. 5 from Enya et al., 2018
whole organism bile alcohol decreased amount, abnormal	control	Fig. 6 , Fig. 7 from Enya et al., 2018

CITATIONS (1)