ZFIN ID: ZDB-FISH-160629-2
Fish name: AB + MO4-thrb
Genotype: AB
Targeting Reagent: MO4-thrb
HUMAN DISEASE MODELED by AB + MO4-thrb
Human Disease Conditions Citations
thyroid hormone resistance syndrome standard conditions Marelli et al., 2016
GENE EXPRESSION
Gene expression in AB + MO4-thrb
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab-T4 standard conditions Fig. 7 with image from Marelli et al., 2016
Reporter gene expression No data available
PHENOTYPE
Phenotype in AB + MO4-thrb
Phenotype Conditions Figures
embryo development decreased rate, abnormal standard conditions Fig. S4 with image from Marelli et al., 2016
eye decreased pigmentation, abnormal standard conditions Fig. 3 with imageFig. 5 with image from Marelli et al., 2016
hypophysis tshba expression increased amount, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
hypophysis tshba expression increased distribution, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
hypophysis cell increased volume, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
mandibular arch skeleton has fewer parts of type cartilage element, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016
notochord morphology, abnormal standard conditions Fig. 3 with image from Marelli et al., 2016
post-vent region curved, abnormal standard conditions Fig. 3 with image from Marelli et al., 2016
retina disorganized, abnormal standard conditions Fig. 5 with image from Marelli et al., 2016
retina morphogenesis in camera-type eye disrupted, abnormal standard conditions Fig. 5 with image from Marelli et al., 2016
semicircular canal development disrupted, abnormal standard conditions Fig. 5 with image from Marelli et al., 2016
swim bladder uninflated, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016
thyroid follicle hyperplastic, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle slc5a5 expression increased amount, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle tg expression increased amount, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle ab-t4 labeling increased distribution, abnormal standard conditions Fig. 7 with image from Marelli et al., 2016
thyroid follicle slc5a5 expression increased distribution, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle tg expression increased distribution, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle increased size, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle cell increased amount, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle cell increased volume, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid primordium increased size, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
whole organism dead, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016
whole organism decreased length, abnormal standard conditions Fig. S4 with image from Marelli et al., 2016
whole organism has extra parts of type thyroid follicle, abnormal standard conditions Fig. 7 with image from Marelli et al., 2016
whole organism lacks parts or has fewer parts of type pectoral fin, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016
whole organism lacks parts or has fewer parts of type otolith, abnormal standard conditions Fig. 5 with image from Marelli et al., 2016
whole organism lacks parts or has fewer parts of type semicircular canal, abnormal standard conditions Fig. 5 with image from Marelli et al., 2016

CITATIONS  (1)