ZFIN Fish: li1Tg

ZFIN ID: ZDB-FISH-150901-4081

Fish name:	li1Tg
Genotype:	li1Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by li1Tg
No data available

GENE EXPRESSION
Gene expression in li1Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
elmo1	pronephros	control	Fig. 2 from Sharma et al., 2016
epoa	whole organism	control	Fig. 3 from She et al., 2017
epor	pronephros	control	Fig. 3 from She et al., 2017
lrp4	fin fold pectoral fin bud pectoral fin renal system retina	control	Fig. 2 from Tian et al., 2018
myh9a	pronephric podocyte pronephros mesangial cell	standard conditions	Fig. 1, Fig. 3 from Müller et al., 2011
nphs1	podocyte	control	Fig. 4 from Schnerwitzki et al., 2014
nphs2	whole organism	control	Fig. 3 from She et al., 2017
septin15	pronephric glomerulus pronephric tubule	standard conditions	Fig. 1 from Dash et al., 2014

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-nrp1		regenerating tissue ventricular epicardium	cold damage: cardiac ventricle	Fig. 2 from Lowe et al., 2019
Ab1-tuba		pronephric tubule cilium	control	Fig. 5 from Dash et al., 2014
Ab36-h3		pronephros proximal region	standard conditions	Fig. S8 from Reilly et al., 2018
Ab1-nucleoporin		liver cell pronephric glomerulus	control	Fig. 4 from Cianciolo Cosentino et al., 2019
Ab1-atp1a1		pronephric tubule epithelial cell	control	Fig. 2 from Thomasova et al., 2016
Ab1-nrp1		cardiac ventricle	control	Fig. 2 from Lowe et al., 2019
Ab6-map1lc3b		pronephric duct	control	Fig. 7 from Chang et al., 2017
Ab1-lrp4	lrp4	fin fold pectoral fin bud pectoral fin renal system retina	control	Fig. 2 from Tian et al., 2018
Ab1-myh9	myh9a	pronephric podocyte pronephros mesangial cell	standard conditions	Fig. 1, Fig. 3 from Müller et al., 2011
Ab2-sept7	septin15	pronephric glomerulus pronephric tubule	standard conditions	Fig. 1 from Dash et al., 2014

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
EGFP	(not) cardiac ventricle developing mesonephric nephron exocrine pancreas kidney pharyngeal arch pronephric duct pronephric glomerulus pronephric podocyte pronephric proximal convoluted tubule pronephric proximal straight tubule pronephric tubule pronephros renal system	standard conditions	46 figures from 28 publications
	kidney regenerating tissue pronephric glomerulus pronephric tubule pronephros	chemical treatment: glutamate(1-)	Fig. 5 , Fig. 7 from Li et al., 2020 Fig. 6 from Sharma et al., 2016 Fig. 5 from Le Corre et al., 2014 Fig. 6 from Zhou et al., 2010
	regenerating tissue epicardium	resection: cardiac ventricle, chemical treatment: 4-methylumbelliferone	Fig. 2, Fig. 6 from Lowe et al., 2019 Fig. 5 from Missinato et al., 2015

PHENOTYPE
Phenotype in li1Tg

Phenotype	Conditions	Figures
epicardium epithelial to mesenchymal transition decreased occurrence, abnormal	resection: cardiac ventricle, chemical treatment: 4-methylumbelliferone	Fig. 5 from Missinato et al., 2015
kidney EGFP expression increased amount, abnormal	chemical treatment by injection: gentamycin, chemical ablation: kidney	Fig. 6 from Zhou et al., 2010
pronephric duct morphology, abnormal	chemical treatment: GS4012	Fig. 5 from Chen et al., 2015
pronephric duct morphology, normal	standard conditions	Fig. 2 from She et al., 2019
pronephric glomerulus cystic, abnormal	chemical treatment: GS4012	Fig. 5 from Chen et al., 2015
pronephric glomerulus width, normal	chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F	Fig. 6 from Sharma et al., 2016
pronephric tubule cystic, abnormal	chemical treatment: GS4012	Fig. 5 from Chen et al., 2015
pronephric tubule length, normal	chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F	Fig. 6 from Sharma et al., 2016
pronephros renal filtration occurrence, normal	chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F	Fig. 6 from Sharma et al., 2016
pronephros development disrupted, abnormal	chemical treatment: GS4012	Fig. 5 from Chen et al., 2015
pronephros morphogenesis process quality, normal	chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F	Fig. 6 from Sharma et al., 2016
regenerating tissue epithelial to mesenchymal transition decreased occurrence, abnormal	resection: cardiac ventricle, chemical treatment: 4-methylumbelliferone	Fig. 5 from Missinato et al., 2015
renal glomerulus increased length, abnormal	chemical treatment: glutamate(1-)	Fig. 5 from Li et al., 2020
renal glomerulus increased size, abnormal	chemical treatment: glutamate(1-)	Fig. 5 from Li et al., 2020
renal glomerulus normal size, normal	standard conditions	Fig. 2 from She et al., 2019
renal glomerulus glomerular filtration decreased rate, abnormal	chemical treatment by injection: dextran, chemical treatment: glutamate(1-)	Fig. 5 from Li et al., 2020
renal glomerulus glomerular filtration normal rate, normal	chemical treatment by injection: dextran	Fig. 3 from Li et al., 2020

CITATIONS (56)