ZFIN ID: ZDB-FISH-150901-29186
Fish name: WT + MO1-exosc3
Genotype: WT
Targeting Reagent: MO1-exosc3
HUMAN DISEASE MODELED by WT + MO1-exosc3
Human Disease Conditions Citations
pontocerebellar hypoplasia type 1B standard conditions Francois-Moutal et al., 2018
GENE EXPRESSION
Gene expression in WT + MO1-exosc3
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in WT + MO1-exosc3
Phenotype Conditions Figures
brain decreased size, abnormal standard conditions Fig. 3 from Wan et al., 2012
locomotion decreased process quality, abnormal standard conditions Fig. 3 from Wan et al., 2012
spinal cord curved, abnormal standard conditions Fig. 3 from Wan et al., 2012
vertebral column curved lateral, abnormal standard conditions Fig. 8 from Francois-Moutal et al., 2018
vertebral column decreased length, abnormal standard conditions Fig. 8 from Francois-Moutal et al., 2018
whole organism atxn1b expression increased amount, abnormal standard conditions Fig. 11 from Francois-Moutal et al., 2018
whole organism movement quality, abnormal standard conditions Fig. 3 from Wan et al., 2012
whole organism viability, abnormal standard conditions Fig. 8 from Francois-Moutal et al., 2018

CITATIONS  (3)