ZFIN ID: ZDB-FISH-150901-23358
Fish name: ndr2Df(Chr12:hhex)b16/b16 (AB)
Genotype: ndr2Df(Chr12:hhex)b16/b16 (AB)
Targeting Reagent: none
HUMAN DISEASE MODELED by ndr2Df(Chr12:hhex)b16/b16 (AB)
No data available
GENE EXPRESSION
Gene expression in ndr2Df(Chr12:hhex)b16/b16 (AB)
RNA expression
Expressed Gene Structure Conditions Figures
ascl1a standard conditions Fig. 7 with imageFig. 8 with imageFig. 9 with image from Allende et al., 1994
ascl1b standard conditions Fig. 7 with imageFig. 9 with imageFig. 10 with image from Allende et al., 1994
col2a1a standard conditions text only from Yan et al., 1995
dbx1a standard conditions text only from Holzschuh et al., 2003
dlx2a standard conditions text only from Holzschuh et al., 2003
egr2b standard conditions Fig. 5 with image from Varga et al., 1999
en2b standard conditions Fig. 5 with image from Varga et al., 1999
foxa1 standard conditions text only from Elsalini et al., 2003
foxa2 standard conditions Fig. 7 with image from Barth et al., 1995
Fig. 9 from Strähle et al., 1993
foxb1a standard conditions Fig. 3 with imageFig. 5 with image from Varga et al., 1999
gdf6b standard conditions text only from Bruneau et al., 1997
hhex standard conditions Fig. 4 with imageFig. 6 with image from Bischof et al., 2004
text only from Elsalini et al., 2003
lhx5 standard conditions text only from Toyama et al., 1995
nkx2.2a standard conditions Fig. 7 with image from Barth et al., 1995
nkx2.4b standard conditions text only from Elsalini et al., 2003
ntn1b standard conditions Fig. 5 from Strähle et al., 1997
pax2a standard conditions text only from Elsalini et al., 2003
Fig. 5 with image from Varga et al., 1999
pax6a standard conditions Fig. 9 from Strähle et al., 1993
shha standard conditions text only from Holzschuh et al., 2003
Fig. 7 with image from Barth et al., 1995
tal1 standard conditions text only from Liao et al., 2000
th standard conditions text only from Holzschuh et al., 2003
wnt4b standard conditions Fig. 3 from Liu et al., 2000
wnt8a standard conditions Fig. 6 with image from Bischof et al., 2004
zic1 standard conditions Fig. 3 with image from Varga et al., 1999
Protein expression
Antibody Antigen Genes Structure Conditions Figures
zn-5 standard conditions Fig. 3 from Hatta et al., 1991
Reporter gene expression No data available
PHENOTYPE
Phenotype in ndr2Df(Chr12:hhex)b16/b16 (AB)
Phenotype Conditions Figures
brain quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
brain medial region decreased size, abnormal standard conditions Table 1 from Brand et al., 1996
diencephalon decreased size, abnormal standard conditions Table 1 from Brand et al., 1996
diencephalon physical object quality, abnormal standard conditions Fig. 5 with image from Varga et al., 1999
eye decreased distance eye, abnormal standard conditions Table 1 from Brand et al., 1996
eye fused with eye, abnormal standard conditions Table 1 from Lewis et al., 2001
Fig. 2 from Hatta et al., 1991
eye quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
floor plate aplastic, abnormal standard conditions Table 1 from Brand et al., 1996
floor plate quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
floor plate development arrested, abnormal standard conditions Fig. 3 from Hatta et al., 1991
forebrain quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
forebrain ventral region ascl1a expression absent, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
forebrain ventral region aplastic, abnormal standard conditions text only from Hatta et al., 1991
forebrain ventral region ascl1b expression decreased distribution, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
hindbrain ascl1b expression spatial pattern, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
hindbrain posterior region lacks all parts of type floor plate, abnormal standard conditions Fig. 3 from Hatta et al., 1991
midbrain dorsal region ascl1b expression increased distribution, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
midbrain posterior region ascl1a expression decreased distribution, abnormal standard conditions Fig. 9 with image from Allende et al., 1994
midbrain ventral region ascl1a expression absent, abnormal standard conditions Fig. 7 with imageFig. 8 with image from Allende et al., 1994
midbrain ventral region ascl1b expression decreased distribution, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
midbrain ventral region ascl1b expression increased distribution, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
nervous system quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
olfactory placode fused with olfactory placode, abnormal standard conditions text only from Hatta et al., 1991
optic tectum ascl1b expression increased distribution, abnormal standard conditions Fig. 9 with image from Allende et al., 1994
pharyngeal arch 3-7 skeleton quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
post-vent region curved, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
post-vent region curved ventral, abnormal standard conditions Table 1 from Brand et al., 1996
prechordal plate hypoplastic, abnormal standard conditions Table 1 from Brand et al., 1996
primary motor neuron decreased amount, abnormal standard conditions Table 1 from Lewis et al., 2001
retinal ganglion cell axon guidance disrupted, abnormal standard conditions Table 1 from Brand et al., 1996
retinal ganglion cell axon guidance quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
rhombomere dorsal region ascl1b expression spatial pattern, abnormal standard conditions Fig. 10 with image from Allende et al., 1994
rhombomere ventral region ascl1b expression absent, abnormal standard conditions Fig. 10 with image from Allende et al., 1994
rhombomere 1 ventral region ascl1a expression absent, abnormal standard conditions Fig. 7 with imageFig. 8 with image from Allende et al., 1994
rhombomere 2 ventral region ascl1b expression absent, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
rhombomere 3 ventral region ascl1b expression absent, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
rhombomere 4 ventral region ascl1b expression absent, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
rhombomere 6 ventral region ascl1b expression absent, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
sensory system quality, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
spinal cord ascl1b expression increased distribution, abnormal standard conditions Fig. 7 with image from Allende et al., 1994
spinal cord lacks all parts of type floor plate, abnormal standard conditions Fig. 3 from Hatta et al., 1991
tegmentum ascl1a expression absent, abnormal standard conditions Fig. 8 with imageFig. 9 with image from Allende et al., 1994
tegmentum anterior region ascl1b expression increased distribution, abnormal standard conditions Fig. 10 with image from Allende et al., 1994
tegmentum posterior region ascl1b expression decreased distribution, abnormal standard conditions Fig. 10 with image from Allende et al., 1994
tegmentum ventral-most region ascl1b expression decreased distribution, abnormal standard conditions Fig. 9 with image from Allende et al., 1994
whole organism curved ventral, abnormal standard conditions Fig. 2 from Hatta et al., 1991
whole organism lethal (sensu genetics), abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
whole organism shape, abnormal standard conditions Fig. for (b16) with image from Phenotype Annotation (1994-2006)
whole organism viability, abnormal standard conditions text only from Hatta et al., 1991

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