ZFIN ID: ZDB-FISH-150901-1892
Fish name: WT + MO1-tnnt2a
Genotype: WT
Targeting Reagent: MO1-tnnt2a
HUMAN DISEASE MODELED by WT + MO1-tnnt2a
No data available
GENE EXPRESSION
Gene expression in WT + MO1-tnnt2a
RNA expression
Expressed Gene Structure Conditions Figures
acana standard conditions Fig. 1 from Rambeau et al., 2017
bmp10 standard conditions Fig. S4 with image from Laux et al., 2013
bmp10l standard conditions Fig. S4 with image from Laux et al., 2013
cdh5 standard conditions Fig. 1 with image from Laux et al., 2013
Fig. 2,  Fig. 3 from Nicoli et al., 2010
cxcr4a standard conditions Fig. 1 with image from Laux et al., 2013
Fig. 6 with image from Bussmann et al., 2011
dbh standard conditions Fig. 7 with image from Chou et al., 2014
dll4 standard conditions Fig. 4 from Wang et al., 2011
dre-mir-21-1 chemical treatment: pharmaceutical Fig. 3 from Banjo et al., 2013
standard conditions Fig. 2 from Banjo et al., 2013
edn1 standard conditions Fig. 1 with image from Laux et al., 2013
efnb2a standard conditions Fig. 4 from Wang et al., 2011
Fig. S6 from Herpers et al., 2008
flt1 standard conditions Fig. 1 from Fontana et al., 2020
flt4 standard conditions Fig. 1 from Fontana et al., 2020
Fig. 2,  Fig. S6 from Herpers et al., 2008
foxc1a control Fig. 6 with image from Chen et al., 2017
foxc1b control Fig. 6 with image from Chen et al., 2017
gata1a standard conditions Fig. 1 from Wang et al., 2011
heg1 standard conditions Fig. 1 from Fontana et al., 2020
Fig. 1 with image from Donat et al., 2018
ifng1 standard conditions Fig. 5 with image from Sawamiphak et al., 2014
kdr standard conditions Fig. 1 from Fontana et al., 2020
kdrl standard conditions Fig. 1 from Fontana et al., 2020
Fig. 5 from Xie et al., 2018
Fig. 6 with image from Bussmann et al., 2011
klf2a standard conditions Fig. 4 from Xie et al., 2018
Fig. S1 with image from Novodvorsky et al., 2015
Fig. 5 with image from Renz et al., 2015
Fig. 5 from Wang et al., 2011
Fig. 2 from Nicoli et al., 2010
klf2b standard conditions Fig. 5 with image from Renz et al., 2015
krit1 standard conditions Fig. 1 with image from Donat et al., 2018
mir126a standard conditions Fig. 3 from Nicoli et al., 2010
mpx standard conditions Fig. S2 with image from Glenn et al., 2014
myb standard conditions Fig. S5 with image from Novodvorsky et al., 2015
Fig. 2 from Wang et al., 2011
notch1b standard conditions Fig. 1 from Fontana et al., 2020
nphs1 standard conditions Fig. 7 with image from Ichimura et al., 2012
nr5a1a standard conditions Fig. 7 with image from Chou et al., 2014
rag1 standard conditions Fig. 2 from Wang et al., 2011
runx1 chemical treatment: S-nitroso-N-acetyl-D-penicillamine Fig. 7 from Wang et al., 2011
standard conditions Fig. S5 with image from Novodvorsky et al., 2015
Fig. 5 with image from Sawamiphak et al., 2014
Fig. 2,  Fig. 7 from Wang et al., 2011
tal1 standard conditions Fig. 1 from Wang et al., 2011
tcf21 standard conditions Fig. 6 with image from Serluca, 2008
wt1a standard conditions Fig. 6 with image from Serluca, 2008
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in WT + MO1-tnnt2a
Phenotype Conditions Figures
adrenal gland development process quality, abnormal standard conditions Fig. 7 with image from Chou et al., 2014
anterior cardinal vein unlumenized, abnormal standard conditions Fig. 1 from Herbert et al., 2009
artery morphogenesis delayed, abnormal standard conditions Fig. 4 from Wang et al., 2011
basibranchial condensed, abnormal standard conditions Fig. 4 with image from Anderson et al., 2008
blood accumulation trunk, abnormal standard conditions Fig. 2 from Wang et al., 2011
blood circulation arrested, abnormal standard conditions Fig. 1 with image from Donat et al., 2018
Fig. 6 with image from Bussmann et al., 2011
Fig. 1 from Herbert et al., 2009
brain vasculature hemorrhagic, abnormal standard conditions Fig. S1 with image from Mugoni et al., 2013
cardiac muscle cell decreased size, normal standard conditions Fig. 7 from Yang et al., 2012
cardiac muscle cell electric potential, abnormal standard conditions Fig. 4 with image from Becker et al., 2011
cardiac muscle cell sarcomere disorganized, abnormal standard conditions Fig. 7 from Yang et al., 2012
caudal vein plexus klf2a expression decreased distribution, abnormal standard conditions Fig. 4 from Xie et al., 2018
caudal vein plexus kdrl expression decreased distribution, abnormal control Fig. 5 from Xie et al., 2018
central artery physical object quality, abnormal standard conditions Fig. 6 with image from Bussmann et al., 2011
ceratobranchial cartilage orientation ceratobranchial cartilage, abnormal standard conditions Fig. 4 with image from Anderson et al., 2008
ceratohyal cartilage orientation ceratohyal cartilage, abnormal standard conditions Fig. 4 with image from Anderson et al., 2008
chromaffin cell mislocalised, abnormal standard conditions Fig. 7 with image from Chou et al., 2014
common cardinal vein blood vessel endothelial cell decreased amount, abnormal standard conditions Fig. 8 with image from Helker et al., 2013
dorsal aorta dilated, abnormal standard conditions Fig. 4 with image,  Fig. 7 with image from Ichimura et al., 2012
dorsal aorta lumenized, normal standard conditions Fig. 4 from Wang et al., 2011
Fig. 4 with image from Jin et al., 2007
dorsal aorta unlumenized, abnormal standard conditions Fig. 4 from Wang et al., 2011
endocardium morphology, normal standard conditions Fig. 6 with image from Serluca, 2008
endothelial cell amount, normal standard conditions Fig. 4 with image from Jin et al., 2007
heart heg1 expression decreased amount, abnormal standard conditions Fig. 1 from Fontana et al., 2020
heart flt1 expression decreased amount, abnormal standard conditions Fig. 1 from Fontana et al., 2020
heart notch1b expression decreased amount, abnormal standard conditions Fig. 1 from Fontana et al., 2020
heart flt4 expression increased amount, abnormal standard conditions Fig. 1 from Fontana et al., 2020
heart morphology, abnormal standard conditions Fig. S1 with image from Mugoni et al., 2013
hematopoietic multipotent progenitor cell decreased amount, abnormal standard conditions Fig. 7 from Wang et al., 2011
hematopoietic multipotent progenitor cell normal amount, normal chemical treatment: S-nitroso-N-acetyl-D-penicillamine Fig. 7 from Wang et al., 2011
interrenal gland animal organ morphogenesis process quality, abnormal standard conditions Fig. 7 with image from Chou et al., 2014
nitric oxide biosynthetic process disrupted, abnormal standard conditions Fig. 7 from Wang et al., 2011
nucleate erythrocyte development disrupted, abnormal standard conditions Fig. 8 with image from Helker et al., 2013
palatoquadrate arch decreased length, abnormal standard conditions Fig. 4 with image from Anderson et al., 2008
pericardium edematous, abnormal standard conditions Fig. 6 with image from Serluca, 2008
posterior cardinal vein lumenized, normal standard conditions Fig. 4 with image from Jin et al., 2007
posterior cardinal vein unlumenized, abnormal standard conditions Fig. 1 from Herbert et al., 2009
primitive erythrocyte differentiation process quality, normal standard conditions Fig. 1 from Wang et al., 2011
pronephric glomerulus disorganized, abnormal standard conditions Fig. 6 with image,  Fig. 7 with image from Ichimura et al., 2012
pronephric glomerulus hypoplastic, abnormal standard conditions Fig. 4 with image,  Fig. 7 with image from Ichimura et al., 2012
pronephric glomerulus lacks all parts of type pronephric glomerular capillary, abnormal standard conditions Fig. 4 with image from Ichimura et al., 2012
pronephric glomerulus morphology, abnormal standard conditions Fig. 4 with image from Ichimura et al., 2012
pronephric glomerulus unfused from pronephric glomerulus, abnormal standard conditions Fig. 4 with image,  Fig. 7 with image from Ichimura et al., 2012
pronephric podocyte nphs1 expression spatial pattern, abnormal standard conditions Fig. 7 with image from Ichimura et al., 2012
pronephric podocyte podocyte foot present, normal standard conditions Fig. 6 with image from Ichimura et al., 2012
pronephric podocyte slit diaphragm present, normal standard conditions Fig. 6 with image from Ichimura et al., 2012
pronephros development process quality, abnormal standard conditions Fig. 4 with image from Ichimura et al., 2012
regulation of cardiac muscle contraction by calcium ion signaling disrupted, abnormal standard conditions Fig. 4 with image from Becker et al., 2011
sprouting angiogenesis process quality, abnormal standard conditions Fig. 6 with image from Bussmann et al., 2011
thymus decreased size, abnormal standard conditions Fig. 2 from Wang et al., 2011
thymus hematopoietic multipotent progenitor cell decreased amount, abnormal standard conditions Fig. 2 from Wang et al., 2011
trunk hematopoietic multipotent progenitor cell decreased amount, abnormal standard conditions Fig. 2,  Fig. 5 from Wang et al., 2011
trunk vasculature klf2a expression decreased amount, abnormal standard conditions Fig. S1 with image from Novodvorsky et al., 2015
venous blood vessel morphogenesis disrupted, abnormal standard conditions Fig. 1 from Herbert et al., 2009
ventral wall of dorsal aorta hematopoietic stem cell runx1 expression decreased amount, abnormal standard conditions Fig. S5 with image from Novodvorsky et al., 2015
ventral wall of dorsal aorta hematopoietic stem cell myb expression decreased amount, abnormal standard conditions Fig. S5 with image from Novodvorsky et al., 2015
ventricular myocardium decreased volume, normal standard conditions Fig. 7 from Yang et al., 2012
whole organism foxc1b expression decreased amount, abnormal control Fig. 6 with image from Chen et al., 2017
whole organism heg1 expression decreased amount, abnormal standard conditions Fig. 1 with image from Donat et al., 2018
whole organism foxc1a expression decreased amount, abnormal control Fig. 6 with image from Chen et al., 2017

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