ZFIN Fish: WT + MO2-rtn4b

ZFIN ID: ZDB-FISH-150901-16492

ZFIN ID: ZDB-FISH-150901-16492

Fish name:	WT + MO2-rtn4b
Genotype:	WT
Targeting Reagent:	MO2-rtn4b

HUMAN DISEASE MODELED by WT + MO2-rtn4b
No data available

GENE EXPRESSION
Gene expression in WT + MO2-rtn4b

RNA expression

Expressed Gene	Structure	Conditions	Figures
rtn4b	retina	transection: cranial nerve II	Fig. 4 from Welte et al., 2015

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-elavl		brain neuron forebrain neuron optic tectum neuron	standard conditions	Fig. 7 from Pinzón-Olejua et al., 2014
Ab2-alcama		cranial nerve II retinal ganglion cell axon	standard conditions	Fig. 6 from Pinzón-Olejua et al., 2014
Ab1-rtn4b	rtn4b	retina	transection: cranial nerve II	Fig. 4 from Welte et al., 2015

Reporter gene expression No data available

PHENOTYPE
Phenotype in WT + MO2-rtn4b

Phenotype	Conditions	Figures
brain decreased size, abnormal	standard conditions	Fig. 4 , Fig. 7 from Pinzón-Olejua et al., 2014
caudal fin curved ventral, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
caudal fin decreased thickness, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
cranial nerve II has fewer parts of type retinal ganglion cell axon, abnormal	standard conditions	Fig. 6 from Pinzón-Olejua et al., 2014
cranial nerve II axon regeneration disrupted, abnormal	transection: cranial nerve II	Fig. 6 from Welte et al., 2015
eye decreased size, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
forebrain decreased size, abnormal	standard conditions	Fig. 7 from Pinzón-Olejua et al., 2014
forebrain flattened, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
fourth ventricle deformed, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
head decreased size, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
immature eye decreased size, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
notochord curved, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
olfactory placode morphology, abnormal	standard conditions	Fig. 7 from Pinzón-Olejua et al., 2014
optic tectum decreased size, abnormal	standard conditions	Fig. 7 from Pinzón-Olejua et al., 2014
optic tectum has fewer parts of type retinal ganglion cell neuron projection, abnormal	standard conditions	Fig. 7 from Pinzón-Olejua et al., 2014
optic tectum mislocalised anteriorly, abnormal	standard conditions	Fig. 7 from Pinzón-Olejua et al., 2014
pericardial cavity inflated, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014
retina has fewer parts of type retinal ganglion cell, abnormal	standard conditions	Fig. 6 from Pinzón-Olejua et al., 2014
retinal ganglion cell axon guidance process quality, abnormal	standard conditions	Fig. 6 from Pinzón-Olejua et al., 2014
ventral mandibular arch absent, abnormal	standard conditions	Fig. 4 from Pinzón-Olejua et al., 2014

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