ZFIN Fish: WT + MO1-hsf1

ZFIN ID: ZDB-FISH-150901-12783

ZFIN ID: ZDB-FISH-150901-12783

Fish name:	WT + MO1-hsf1
Genotype:	WT
Targeting Reagent:	MO1-hsf1

HUMAN DISEASE MODELED by WT + MO1-hsf1
No data available

GENE EXPRESSION
Gene expression in WT + MO1-hsf1

RNA expression

Expressed Gene	Structure	Conditions	Figures
cdh1	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014
foxd3	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014
hsf1	(not) brain (not) retina	control	Fig. 5 from Kashyap et al., 2014
hsp70l	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014
hsp90aa1.2	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014
hspa8	whole organism	heat exposure	Fig. 5 from Gong et al., 2019
hsph1	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014
snai1b	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014
snai2	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014
tfap2a	whole organism	standard conditions	Fig. 6 from Eroglu et al., 2014

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-elavl		diencephalon midbrain telencephalon	hypoxia, heat shock	Fig. 5 from Tucker et al., 2011
Ab1-hspb1		whole organism	standard conditions	Fig. 6 from Tucker et al., 2011
Ab1-hsp70		whole organism	standard conditions	Fig. 6 from Tucker et al., 2011
Ab1-elavl		diencephalon midbrain telencephalon	standard conditions	Fig. 5 from Tucker et al., 2011
Ab1-hsp70		whole organism	hypoxia, heat shock	Fig. 4 , Fig. 6 from Tucker et al., 2011
Ab1-hspb1		whole organism	hypoxia, heat shock	Fig. 4 , Fig. 6 from Tucker et al., 2011
Ab1-hsf1		whole organism	standard conditions	Fig. 4 from Tucker et al., 2011
Ab2-hsf1	hsf1	(not) brain (not) retina	control	Fig. 5 from Kashyap et al., 2014

Reporter gene expression No data available

PHENOTYPE
Phenotype in WT + MO1-hsf1

Phenotype	Conditions	Figures
brain hsf1 expression absent, abnormal	control	Fig. 5 from Kashyap et al., 2014
eye decreased circumference, abnormal	control	Fig. 6 from Kashyap et al., 2014
eye decreased circumference, abnormal	chemical treatment by environment: ethanol	Fig. 6 from Kashyap et al., 2014
eye decreased diameter, abnormal	standard conditions	Fig. 2 from Evans et al., 2007
eye decreased size, abnormal	standard conditions	Fig. 1, Fig. 6, text only from Evans et al., 2007
lens decreased circumference, abnormal	chemical treatment by environment: ethanol	Fig. 6 from Kashyap et al., 2014
lens decreased size, abnormal	standard conditions	Fig. 3, Fig. 6 from Evans et al., 2007
lens immature, abnormal	standard conditions	Fig. 3 from Evans et al., 2007
lens structure, abnormal	standard conditions	Fig. 6 from Evans et al., 2007
pupil decreased diameter, abnormal	standard conditions	Fig. 2 from Evans et al., 2007
response to heat disrupted, abnormal	heat shock	Fig. 5 from Evans et al., 2007
retina hsf1 expression absent, abnormal	control	Fig. 5 from Kashyap et al., 2014
retina decreased size, abnormal	standard conditions	Fig. 3 from Evans et al., 2007
retina disorganized, abnormal	standard conditions	Fig. 3 from Evans et al., 2007
retina structure, abnormal	standard conditions	Fig. 6 from Evans et al., 2007
retinal ganglion cell decreased amount, abnormal	standard conditions	Fig. 6 from Evans et al., 2007
whole organism hspa8 expression amount, ameliorated	heat exposure	Fig. 5 from Gong et al., 2019
whole organism tfap2a expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism snai1b expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism cdh1 expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism snai2 expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism foxd3 expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism hsp90aa1.2 expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism hsp70l expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism hsph1 expression decreased amount, abnormal	standard conditions	Fig. 6 from Eroglu et al., 2014
whole organism length, normal	standard conditions	Fig. 2 from Evans et al., 2007

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