ZFIN ID: ZDB-FISH-150901-10196
Fish name: tp53zdf1/zdf1
Genotype: tp53zdf1/zdf1
Targeting Reagent: none
HUMAN DISEASE MODELED by tp53zdf1/zdf1
No data available
GENE EXPRESSION
Gene expression in tp53zdf1/zdf1
RNA expression
Expressed Gene Structure Conditions Figures
baxa standard conditions Fig. 3 with image from Berghmans et al., 2005
gamma ray Fig. 7 from Lee et al., 2008
Fig. 3 with image from Berghmans et al., 2005
ccng1 radiation, chemical treatment: seliciclib Fig. 7 from Lee et al., 2008
cdkn1a radiation, chemical treatment: seliciclib Fig. 7 from Lee et al., 2008
dlx2a control Fig. 3 with image from Boer et al., 2016
foxd3 control Fig. 3 with image from Boer et al., 2016
gata5 standard conditions Fig. 6 from Liu et al., 2017
gfap standard conditions Fig. 10 with image from Berghmans et al., 2005
h2ax standard conditions Fig. S10 with image from Sidi et al., 2008
chemical treatment: Goe 6976 Fig. S10 with image from Sidi et al., 2008
radiation Fig. S10 with image from Sidi et al., 2008
hsf1 heat exposure Fig. 5 from Gong et al., 2019
hsp70.3 heat exposure Fig. S2 from Gong et al., 2019
hspa4l heat exposure Fig. S2 from Gong et al., 2019
hspa8 heat exposure Fig. 5,  Fig. S2 from Gong et al., 2019
hspb1 heat exposure Fig. S2 from Gong et al., 2019
hspb8 heat exposure Fig. S2 from Gong et al., 2019
hspd1 heat exposure Fig. S2 from Gong et al., 2019
hsph1 heat exposure Fig. S2 from Gong et al., 2019
lcp1 radiation Fig. 2 with image from Sidi et al., 2008
mdm2 standard conditions Fig. 3 with image from Berghmans et al., 2005
gamma ray Fig. 7 from Lee et al., 2008
Fig. 3 with image from Berghmans et al., 2005
mpx radiation Fig. 2 with image from Sidi et al., 2008
myb control Fig. 5 with image from He et al., 2017
Fig. 5 with image from Imamura et al., 2008
mybl2a standard conditions Fig. 5 from Pereboom et al., 2011
neurog1 standard conditions Fig. S5 with image from Liu et al., 2016
otx2b standard conditions Fig. 7 with image,  Fig. S5 with image from Liu et al., 2016
pak2a standard conditions Fig. 3 with image from Berghmans et al., 2005
gamma ray Fig. 3 with image from Berghmans et al., 2005
runx1 standard conditions Fig. 5 from Pereboom et al., 2011
Fig. 5 with image from Imamura et al., 2008
slc4a1a radiation Fig. 2 with image from Sidi et al., 2008
sox10 control Fig. 3 with image from Boer et al., 2016
th control Fig. 4 with image from Boer et al., 2016
tp53 standard conditions Fig. 5 from Lee et al., 2008
Fig. 3 with image from Berghmans et al., 2005
chemical treatment: seliciclib Fig. 5 from Lee et al., 2008
gamma ray Fig. 1 from Gong et al., 2019
Fig. 5 from Lee et al., 2008
Fig. 3 with image from Berghmans et al., 2005
Reporter gene expression No data available
PHENOTYPE
Phenotype in tp53zdf1/zdf1
Phenotype Conditions Figures
apoptotic process disrupted, abnormal radiation Fig. S4 with image from Sidi et al., 2008
blood cell normal amount, normal control Fig. 5 with image from Imamura et al., 2008
central nervous system nucleus apoptotic, abnormal radiation, chemical treatment: Goe 6976 Fig. 3 with image,  Fig. S2 with image from Sidi et al., 2008
central nervous system nucleus structure, normal radiation Fig. 3 with image from Sidi et al., 2008
embryo development process quality, normal standard conditions Fig. 2 with image from Sidi et al., 2008
hepatocyte quality, normal standard conditions Fig. 2 with image from Lu et al., 2013
intrinsic apoptotic signaling pathway in response to DNA damage disrupted, abnormal radiation, chemical treatment: protein kinase inhibitor Fig. 7 with image from Sidi et al., 2008
intrinsic apoptotic signaling pathway in response to DNA damage disrupted, abnormal radiation Fig. 2 with image from Sidi et al., 2008
intrinsic apoptotic signaling pathway in response to DNA damage disrupted, abnormal radiation, chemical treatment: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor Fig. 7 with image from Sidi et al., 2008
intrinsic apoptotic signaling pathway in response to DNA damage disrupted, abnormal radiation Fig. 7 with image from Sidi et al., 2008
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator disrupted, abnormal radiation Fig. 1 with image from Sidi et al., 2008
presumptive endoderm gata5 expression decreased amount, abnormal standard conditions Fig. 6 from Liu et al., 2017
response to gamma radiation process quality, abnormal radiation Fig. 1 with image from Sidi et al., 2008
whole organism apoptotic, abnormal radiation, chemical treatment: Goe 6976 Fig. 7 with image from Sidi et al., 2008
whole organism decreased life span, ameliorated heat exposure Fig. 1 from Gong et al., 2019
whole organism decreased life span, exacerbated heat exposure Fig. 1 from Gong et al., 2019
whole organism decreased sensitivity to irradiation, abnormal radiation Fig. 1 with image,  Fig. 2 with image from Sidi et al., 2008
whole organism hspb8 expression increased amount, abnormal heat exposure Fig. S2 from Gong et al., 2019
whole organism hsp70.3 expression increased amount, abnormal heat exposure Fig. S2 from Gong et al., 2019
whole organism hsf1 expression increased amount, abnormal heat exposure Fig. 5 from Gong et al., 2019
whole organism hsph1 expression increased amount, abnormal heat exposure Fig. S2 from Gong et al., 2019
whole organism tp53 expression increased amount, abnormal heat exposure Fig. 1 from Gong et al., 2019
whole organism hspa8 expression increased amount, abnormal heat exposure Fig. 5,  Fig. S2 from Gong et al., 2019
whole organism tp53 expression increased amount, abnormal heat exposure Fig. 1 from Gong et al., 2019
whole organism hspa4l expression increased amount, abnormal heat exposure Fig. S2 from Gong et al., 2019
whole organism hspd1 expression increased amount, abnormal heat exposure Fig. S2 from Gong et al., 2019
whole organism hspb1 expression increased amount, abnormal heat exposure Fig. S2 from Gong et al., 2019
whole organism structure, normal radiation, chemical treatment: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor Fig. 7 with image from Sidi et al., 2008
whole organism structure, normal radiation Fig. 7 with image from Sidi et al., 2008
whole organism structure, normal radiation Fig. 1 with image,  Fig. 2 with image from Sidi et al., 2008
whole organism structure, normal chemical treatment: Goe 6976 Fig. 7 with image from Sidi et al., 2008
whole organism structure, normal radiation, chemical treatment: protein kinase inhibitor Fig. 7 with image from Sidi et al., 2008
whole organism structure, normal standard conditions Fig. 3 with image,  Fig. 7 with image from Sidi et al., 2008

CITATIONS  (20)

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