Engineered Foreign Gene
GtACR2
- ID
- ZDB-EFG-200519-2
- Name
- GtACR2
- Symbol
- GtACR2
- Previous Names
- None
- Type
- engineered_foreign_gene
- Location
- Unmapped
- Note
-
light-regulated neuron inhibition tool -GtACR2 corresponds to the light-gated anion channel encoded by the Guillardia theta ACR2 gene (GB_protein:XP_005821982). It can be used as an optogenetic tool to produce membrane hyperpolarization and inhibit neuron activity; it strictly conducts anions, shows rapid response kinetics, and requires low light intensity for activation. The maximal sensitivity of the protein is to 470nm light (PMID:26113638).
Expression
- All Expression Data
- No data available
Constructs
Sequence Information
Citations