CRISPR

CRISPR6-elovl2

ID
ZDB-CRISPR-250604-2
Name
CRISPR6-elovl2
Previous Names
None
Target
Sequence
5' - TGTCAGGCACTGGACGAAGT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
co100 elovl2
co101 elovl2
Expression
Gene expression in Wild Types + CRISPR6-elovl2
No data available
Phenotype
Phenotype resulting from CRISPR6-elovl2
No data available
Phenotype of all Fish created by or utilizing CRISPR6-elovl2
Phenotype Fish Conditions Figures
whole organism arachidonic acid increased amount, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig. S3,  Fig.5 with image,  Fig.6 with image from Ranard et al., 2024
whole organism docosahexaenoic acid amount, exacerbated elovl2co100/co100 (AB) low polyunsaturated fat Fig.5 with image from Ranard et al., 2024
eye decreased size, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig.6 with image from Ranard et al., 2024
swim bladder uninflated, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig.6 with image from Ranard et al., 2024
whole organism fatty acid 14:0 increased amount, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Table 2 from Ranard et al., 2024
whole organism fatty acid 14:0 decreased amount, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Table 2 from Ranard et al., 2024
whole organism arachidonic acid amount, exacerbated elovl2co100/co100 (AB) low polyunsaturated fat Fig.5 with image,  Table 2 from Ranard et al., 2024
whole organism fatty acid 16:1 decreased amount, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Table 2 from Ranard et al., 2024
whole organism docosahexaenoic acid decreased amount, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig. S3,  Fig.5 with image,  Fig.6 with image,  Table 2 from Ranard et al., 2024
retinal cone cell decreased amount, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig.7 with image from Ranard et al., 2024
pericardium edematous, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig.6 with image from Ranard et al., 2024
retinal neural layer disorganized, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig.7 with image from Ranard et al., 2024
post-vent region curved, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig.6 with image from Ranard et al., 2024
retinal neural layer Ab9-calb2 labeling decreased distribution, abnormal elovl2co100/co100 (AB) low polyunsaturated fat Fig.7 with image from Ranard et al., 2024
whole organism docosahexaenoic acid decreased amount, abnormal elovl2co101/co101 (AB) low polyunsaturated fat Fig. S3 from Ranard et al., 2024
whole organism arachidonic acid increased amount, abnormal elovl2co101/co101 (AB) low polyunsaturated fat Fig. S3 from Ranard et al., 2024
Citations
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