CRISPR

CRISPR4-dab2

ID

ZDB-CRISPR-250331-5

Name

CRISPR4-dab2

Previous Names

None

Target

Sequence

5' - GATGATGTTCAAGATGCAAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mu410	dab2

Expression

Gene expression in Wild Types + CRISPR4-dab2

No data available

Phenotype

Phenotype resulting from CRISPR4-dab2

No data available

Phenotype of all Fish created by or utilizing CRISPR4-dab2

Phenotype	Fish	Conditions	Figures
dorsal aorta dab2 expression absent, abnormal	dab2^mu410/mu410	standard conditions	Fig. 2 from Uphoff et al., 2024
posterior cardinal vein dab2 expression absent, abnormal	dab2^mu410/mu410	standard conditions	Fig. 2 from Uphoff et al., 2024
caudal vein plexus sprouting angiogenesis decreased process quality, abnormal	dab2^mu410/+; hu7135Tg	standard conditions	Fig. 3 from Uphoff et al., 2024
caudal vein plexus sprouting angiogenesis decreased process quality, abnormal	dab2^mu410/mu410; hu7135Tg	standard conditions	Fig. 3 from Uphoff et al., 2024
brain lymphatic endothelial cell clathrin-dependent endocytosis decreased process quality, abnormal	dab2^mu410/mu410; hu7135Tg	standard conditions	Fig. 5 from Uphoff et al., 2024
optic tectum primitive meninx has extra parts of type brain lymphatic endothelial cell, abnormal	dab2^mu410/mu410; nz101Tg; y7Tg	standard conditions	Fig. 4 from Uphoff et al., 2024

Citations