CRISPR

CRISPR1-foxp2

ID

ZDB-CRISPR-230615-1

Name

CRISPR1-foxp2

Previous Names

None

Target

foxp2 (1)

Sequence

5' - GGACATGCTGTGATGAGTGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "TGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
wue101	foxp2

Expression

Gene expression in Wild Types + CRISPR1-foxp2

No data available

Phenotype

Phenotype resulting from CRISPR1-foxp2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-foxp2

Phenotype	Fish	Conditions	Figures
whole organism cntnap2b expression increased amount, abnormal	foxp2^{wue101/wue101} (AB)	standard conditions	Fig. 1 from Lüffe et al., 2021
swim bladder uninflated, abnormal	foxp2^{wue101/wue101} (AB)	standard conditions	Fig. 1 from Lüffe et al., 2021
swimming behavior increased process quality, abnormal	foxp2^{wue101/wue101} (AB)	standard conditions	Fig. 2 from Lüffe et al., 2021
whole organism foxp1a expression increased amount, abnormal	foxp2^{wue101/wue101} (AB)	standard conditions	Fig. 1 from Lüffe et al., 2021
whole organism foxp2 expression decreased amount, abnormal	foxp2^{wue101/wue101} (AB)	standard conditions	Fig. 1 from Lüffe et al., 2021
swimming behavior process quality, ameliorated	foxp2^wue101/+ (AB)	chemical treatment by environment: muscimol	Fig. 5 from Lüffe et al., 2021
whole organism gad1b expression decreased amount, abnormal	foxp2^wue101/+ (AB)	standard conditions	Fig. 5 from Lüffe et al., 2021
whole organism cntnap2b expression increased amount, abnormal	foxp2^wue101/+ (AB)	standard conditions	Fig. 1 from Lüffe et al., 2021
swimming behavior increased process quality, abnormal	foxp2^wue101/+ (AB)	control	Fig. 2 , Fig. 5 from Lüffe et al., 2021
swimming behavior increased process quality, abnormal	foxp2^wue101/+ (AB)	chemical treatment by environment: methylphenidate	Fig. 5 from Lüffe et al., 2021
whole organism foxp2 expression decreased amount, abnormal	foxp2^wue101/+ (AB)	standard conditions	Fig. 1 from Lüffe et al., 2021

Citations