CRISPR

CRISPR1-spag6

ID

ZDB-CRISPR-220309-1

Name

CRISPR1-spag6

Previous Names

None

Target

Sequence

5' - GGACGCTCTTGTCATCTCCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ci1013	spag6

Expression

Gene expression in Wild Types + CRISPR1-spag6

No data available

Phenotype

Phenotype resulting from CRISPR1-spag6

No data available

Phenotype of all Fish created by or utilizing CRISPR1-spag6

Phenotype	Fish	Conditions	Figures
determination of heart left/right asymmetry process quality, abnormal	spag6^{ci1013/ci1013}	standard conditions	Fig. 8. from Falkenberg et al., 2021
heart looping disrupted, abnormal	spag6^{ci1013/ci1013}	standard conditions	Fig. 8. from Falkenberg et al., 2021
neutrophil decreased amount, abnormal	spag6^{ci1013/ci1013}	standard conditions	Fig. 8. from Falkenberg et al., 2021
heart mislocalised, abnormal	spag6^{ci1013/ci1013}	standard conditions	Fig. 8. from Falkenberg et al., 2021
heart linear, abnormal	spag6^{ci1013/ci1013}	standard conditions	Fig. 8. from Falkenberg et al., 2021
macrophage decreased amount, abnormal	spag6^{ci1013/ci1013}	standard conditions	Fig. 8. from Falkenberg et al., 2021
myeloid lineage restricted progenitor cell decreased amount, abnormal	spag6^{ci1013/ci1013}; gl21Tg	standard conditions	Fig. 8. from Falkenberg et al., 2021
neutrophil migration decreased efficacy, abnormal	spag6^{ci1013/ci1013}; uwm1Tg	light damage: yolk	Fig. 8. from Falkenberg et al., 2021

Citations