CRISPR

CRISPR1-mecom

ID

ZDB-CRISPR-201203-2

Name

CRISPR1-mecom

Previous Names

None

Target

mecom (1)

Sequence

5' - CCCTGGCAACCCTGGCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
co1005	mecom
co1013	mecom

Expression

Gene expression in Wild Types + CRISPR1-mecom

No data available

Phenotype

Phenotype resulting from CRISPR1-mecom

No data available

Phenotype of all Fish created by or utilizing CRISPR1-mecom

Phenotype	Fish	Conditions	Figures
pharyngeal arch runx2b expression decreased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
pharyngeal arch 3-7 prdm1a expression increased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
pharyngeal arch cartilage col2a1a expression decreased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
opercle decreased size, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
Meckel's cartilage decreased distance palatoquadrate cartilage, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
opercle bone mineralization decreased occurrence, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
cranial cartilage col2a1a expression decreased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
ceratobranchial 5 bone decreased size, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
cranium runx2b expression decreased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
eye prdm1a expression increased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
head prdm1a expression increased amount, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
ceratobranchial 5 bone bone mineralization decreased occurrence, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
Meckel's cartilage hypoplastic, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
head prdm16 expression increased amount, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
trabecula cranii decreased distance trabecula cranii, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
hatching gland prdm1a expression increased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
pectoral fin bud prdm1a expression increased distribution, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
ceratobranchial cartilage hypoplastic, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
palatoquadrate cartilage hypoplastic, abnormal	mecom^{co1005/co1005}	standard conditions	Fig. 1 from Shull et al., 2020
Meckel's cartilage decreased distance palatoquadrate cartilage, abnormal	prdm16^co1006/+; prdm1a^m805/+; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
palatoquadrate cartilage hypoplastic, abnormal	prdm16^co1006/+; prdm1a^m805/+; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage hypoplastic, abnormal	prdm16^co1006/+; prdm1a^m805/+; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
ceratobranchial cartilage aplastic, abnormal	prdm16^co1006/+; prdm1a^m805/m805; mecom^co1005/+	standard conditions	Fig. 3 from Shull et al., 2020
ceratobranchial cartilage aplastic, abnormal	prdm16^co1006/+; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
palatoquadrate cartilage hypoplastic, abnormal	prdm16^co1006/+; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
ethmoid cartilage split, abnormal	prdm16^co1006/+; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage hypoplastic, abnormal	prdm16^co1006/+; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage decreased distance palatoquadrate cartilage, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/+; mecom^co1005/+	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage aplastic/hypoplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/+; mecom^co1005/+	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage decreased distance palatoquadrate cartilage, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/+; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage aplastic/hypoplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/+; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage decreased distance palatoquadrate cartilage, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^co1005/+	standard conditions	Fig. 3 from Shull et al., 2020
ceratobranchial cartilage aplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^co1005/+	standard conditions	Fig. 3 from Shull et al., 2020
ethmoid cartilage split, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^co1005/+	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage aplastic/hypoplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^co1005/+	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage decreased distance palatoquadrate cartilage, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
ceratobranchial cartilage aplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
palatoquadrate cartilage hypoplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
ethmoid cartilage split, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage aplastic/hypoplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020
Meckel's cartilage hypoplastic, abnormal	prdm16^{co1006/co1006}; prdm1a^m805/m805; mecom^{co1005/co1005}	standard conditions	Fig. 3 from Shull et al., 2020

Citations