CRISPR
CRISPR1-rab5c
- ID
- ZDB-CRISPR-201020-2
- Name
- CRISPR1-rab5c
- Previous Names
- None
- Target
- Sequence
-
5' - GGTGGACCAGCGCGGACCAA - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
The PAM site was "CGG" at the 3' end.
- Genome Resources
- None
Target Location
Constructs
No data available
Genomic Features
Expression
Gene expression in Wild Types + CRISPR1-rab5c
No data available
Phenotype
Phenotype resulting from CRISPR1-rab5c
No data available
Phenotype of all Fish created by or utilizing CRISPR1-rab5c
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Citations
- Kempers, L., Wakayama, Y., van der Bijl, I., Furumaya, C., De Cuyper, I.M., Jongejan, A., Kat, M., van Stalborch, A.D., van Boxtel, A.L., Hubert, M., Geerts, D., van Buul, J.D., de Korte, D., Herzog, W., Margadant, C. (2021) The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis. Angiogenesis. 24(3):695-714
- Heng, J., Lv, P., Zhang, Y., Cheng, X., Wang, L., Ma, D., Liu, F. (2020) Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling. PLoS Biology. 18:e3000696
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