CRISPR
CRISPR2-megf6b
- ID
- ZDB-CRISPR-200528-16
- Name
- CRISPR2-megf6b
- Previous Names
- None
- Target
- Sequence
-
5' - TCCTGTATCCGGATGACAGG - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
Targets exon 31. The PAM site was "AGG" at the 3' end. This CRISPR contains the SNP rs514123267.
- Genome Resources
- None
Target Location
Constructs
No data available
Genomic Features
Expression
Gene expression in Wild Types + CRISPR2-megf6b
No data available
Phenotype
Phenotype resulting from CRISPR2-megf6b
No data available
Phenotype of all Fish created by or utilizing CRISPR2-megf6b
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Citations
- Teerlink, C.C., Jurynec, M.J., Hernandez, R., Stevens, J., Hughes, D.C., Brunker, C.P., Rowe, K., Grunwald, D.J., Facelli, J.C., Cannon-Albright, L.A. (2020) A role for the MEGF6 gene in predisposition to osteoporosis. Annals of human genetics. 85(2):58-72
- Hoshijima, K., Jurynec, M.J., Klatt Shaw, D., Jacobi, A.M., Behlke, M.A., Grunwald, D.J. (2019) Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish. Developmental Cell. 51(5):645-657.e4
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