ZFIN CRISPR: CRISPR1-tyr

Target Location

Genome Build: GRCz11Chromosome: 15

Constructs

Genomic Features

Genomic Feature	Affected Genomic Regions
by1	tyr
ck112a	tyr
ck112b	tyr
ihb894	tyr
tud181	tyr

1 - 5 of 7 Show all

Expression

Gene expression in Wild Types + CRISPR1-tyr

No data available

Phenotype

Phenotype resulting from CRISPR1-tyr

Phenotype	Fish	Figures
whole organism decreased pigmentation, abnormal	WT + CRISPR1-tyr	Fig. 2 from Carrington et al., 2015
whole organism degree of pigmentation, abnormal	WT + CRISPR1-tyr	Fig. 3 from Wilk et al., 2017

1 - 2 of 2

Phenotype of all Fish created by or utilizing CRISPR1-tyr

Phenotype	Fish	Conditions	Figures
whole organism melanocyte absent, abnormal	tyr^{ck112a/ck112a}	standard conditions	Fig. 5 from Park et al., 2016
visual behavior process quality, abnormal	tyr^{ck112a/ck112a}	standard conditions	Fig. 6 from Park et al., 2016
eye decreased size, abnormal	tyr^{ck112a/ck112a}	standard conditions	Fig. 5 from Park et al., 2016
whole organism colorless, abnormal	tyr^{ck112a/ck112a}	standard conditions	Fig. 5 from Park et al., 2016
retinal pigmented epithelium unpigmented, abnormal	tyr^{ck112a/ck112a}	standard conditions	Fig. 5 from Park et al., 2016

1 - 5 of 10 Show all

Citations

Include unpublished citations

Krueger, C.J., Dai, Z., Zhu, C., Zhang, B. (2024) Heritable CRISPR Mutagenesis of Essential Maternal Effect Genes as a Simple Tool for Sustained Population Suppression of Invasive Species in a Zebrafish Model. Zebrafish. 21(4):279-286
Locubiche, S., Ordóñez, V., Abad, E., Scotto di Mase, M., Di Donato, V., De Santis, F. (2024) A Zebrafish-Based Platform for High-Throughput Epilepsy Modeling and Drug Screening in F0. International Journal of Molecular Sciences. 25(5):
Ma, J., Zhang, W., Rahimialiabadi, S., Ganesh, N.U., Sun, Z., Parvez, S., Peterson, R.T., Yeh, J.J. (2024) Instantaneous visual genotyping and facile site-specific transgenesis via CRISPR-Cas9 and phiC31 integrase. Biology Open. 13(9):
Mori, Y., Smith, S., Wang, J., Eliora, N., Heikes, K.L., Munjal, A. (2024) Versican controlled by Lmx1b regulates hyaluronate density and hydration for semicircular canal morphogenesis. Development (Cambridge, England). 152(1):
Noonan, H.R., Thornock, A.M., Barbano, J., Xifaras, M.E., Baron, C.S., Yang, S., Koczirka, K., McConnell, A.M., Zon, L.I. (2024) A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma. eLIFE. 13:
Ye, X., Lin, J., Chen, Q., Lv, J., Liu, C., Wang, Y., Wang, S., Wen, X., Lin, F. (2024) An Efficient Vector-Based CRISPR/Cas9 System in Zebrafish Cell Line. Marine biotechnology (New York, N.Y.). 26(3):588-598
Kamimoto, K., Stringa, B., Hoffmann, C.M., Jindal, K., Solnica-Krezel, L., Morris, S.A. (2023) Dissecting cell identity via network inference and in silico gene perturbation. Nature. 614(7949):742-751
Maili, L., Tandon, B., Yuan, Q., Menezes, S., Chiu, F., Hashmi, S.S., Letra, A., Eisenhoffer, G.T., Hecht, J.T. (2023) Disruption of fos causes craniofacial anomalies in developing zebrafish. Frontiers in cell and developmental biology. 11:11418931141893
Wang, X., Zhu, J., Wang, H., Deng, W., Jiao, S., Wang, Y., He, M., Zhang, F., Liu, T., Hao, Y., Ye, D., Sun, Y. (2023) Induced formation of primordial germ cells from zebrafish blastomeres by germplasm factors. Nature communications. 14:79187918
Dixon, S.C., Calder, B.J., Lilya, S.M., Davies, B.M., Martin, A., Peterson, M., Hansen, J.M., Suli, A. (2022) Valproic acid affects neurogenesis during early optic tectum development in zebrafish. Biology Open. 12(1):

1 - 10 of 42

Show