Genomic Feature
b160
- ID
- ZDB-ALT-970730-11
- Name
- b160
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- embryos treated with g-rays
- Lab of Origin
- Kimmel Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 19: 14190079 - 14190080 (GRCz11) (1) Details
- Nucleotide change
- CG/ACAGCT
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 6 bp inserted / 2 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
TTATAAAAAAACATCCCACAATGTAAATAGGTTGTAATAAGAATATGAATAATAAGAATATGTGAATAACTCAATTTTGACAAAAATGTCAGATGGAACCTTATAATTCTAAGGTGACTATATATATATATATATATATGTATAAAAGTGTCCTTAAATGTCATTATGCATGATTACTTGCAATAACCCTAACGGTAAACCTTATTATACATAAAAATTAAAAATAAAGGTAAACACACAAATAATCATACTTTTTAAATCTTGAATAAAATTGGTAACACTATTTTTTTTTCCCCACATTTTGAGAAATTGAGTGAATTTGCTCTTACTGGTGGTAGTGCTGCGGTGGGAGTAATGGCTGGGATATGGAGCAGCTCTGTGGTTCCTCAAGCTGGAGTATCTCTCACAGTACGAACCCGAGGAGTGAACAGGGGCCCCATTGAACTGAGGAGGGCTGCTGCTGGGGCCCATGGGGCCGTTACTGGGCAGGAACCAGCCAC
CG/ACAGCT ACTGTTGGAGGAGGACACAAGTGTTAAATATGCTATAATACTGGGGGGAAGTTTGAGTTGTTTGCAGGATTAATGTTGCTTTACTTACGTTGTGAATATCCAGATTGCTGGTTGTCAGTGCTGTGGTCTGGGACTTCCTTGTGGTCACTTCTGTTGACAGAAACAAATCCTTTTTAGTTAACAATAAATTATTAATTATAAAATAAATTATCAAAACAGGATAAATGAATGGCTAATAATGTGTTTTTCTTTTACCTCTCTTTGGCATCGAGGAAAGCTTTGGCAAAAGGATTGTGTTTGATTTTCAGAGCGGTAATCTGAAAAAAAAGAAAAGAAAAAATCAATATGGAAAGTGCTCAATTTATGCAACATTTTGAGGAAAGAGGCAAAAGACACATCTCAAACACTCACCTCTTCATTCTGATATGCTGTGACTGCAATAAACTGTGTCTCAGGAAAAGACTGACTGCTGATCATTTTCTGAATCCCACCGACTTTCA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| tbxtab160/b160 | Homozygous | ♀+/- ♂+/- | 2 figures  from 2 publications | 9 figures from 7 publications | |
| tbxtab160/b160 | Homozygous | Unknown | Fig. 3 from Mabee et al., 2007 | ||
| tbxtab160/b160 (AB) | Homozygous | ♀+/- ♂+/- | 10 figures from 6 publications | 19 figures from 13 publications | |
| tbxtab160/b160; y1Tg | Complex | Fig. 3 from Helker et al., 2015 | Fig. 3 from Helker et al., 2015 | ||
| tbx16b104/b104; tbxtab160/b160 (AB) | Complex | Fig. 8 from Amack et al., 2007 | |||
| tbxtab160/b160; tdgf1unspecified | Complex | Fig. 8 from Schier et al., 1997 | 4 figures from Schier et al., 1997 | ||
| tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a (AB) | Complex | Fig. 7 from Lekven et al., 2001 |
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Supplemental Information
- Genotyping protocol
- None
- Özelçi, E., Mailand, E., Rüegg, M., Oates, A.C., Sakar, M.S. (2022) Deconstructing body axis morphogenesis in zebrafish embryos using robot-assisted tissue micromanipulation. Nature communications. 13:79347934
- Grimes, D.T., Patterson, V.L., Luna-Arvizu, G., Schottenfeld-Roames, J., Irons, Z.H., Burdine, R.D. (2019) Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish. Developmental Biology. 459(2):79-86
- Schredelseker, T., Driever, W. (2018) Bsx controls pineal complex development. Development (Cambridge, England). 145(13):
- Helker, C.S., Schuermann, A., Pollmann, C., Chng, S.C., Kiefer, F., Reversade, B., Herzog, W. (2015) The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis. eLIFE. 4
- Araya, C., Tawk, M., Girdler, G.C., Costa, M., Carmona-Fontaine, C., and Clarke, J.D. (2014) Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo. Neural Development. 9(1):9
- Siekmann, A.F., Standley, C., Fogarty, K.E., Wolfe, S.A., and Lawson, N.D. (2009) Chemokine signaling guides regional patterning of the first embryonic artery. Genes & Development. 23(19):2272-2277
- Amack, J.D., Wang, X., and Yost, H.J. (2007) Two T-box genes play independent and cooperative roles to regulate morphogenesis of ciliated Kupffer's vesicle in zebrafish. Developmental Biology. 310(2):196-210
- Gourronc, F., Ahmad, N., Nedza, N., Eggleston, T., and Rebagliati, M. (2007) Nodal activity around Kupffer's vesicle depends on the T-box transcription factors notail and spadetail and on notch signaling. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(8):2131-2146
- Mabee, P.M., Arratia, G., Coburn, M., Haendel, M., Hilton, E.J., Lundberg, J.G., Mayden, R.L., Rios, N., and Westerfield, M. (2007) Connecting evolutionary morphology to genomics using ontologies: a case study from Cypriniformes including zebrafish. Journal of experimental zoology. Part B, Molecular and developmental evolution. 308(5):655-668
- Londin, E.R., Niemiec, J., and Sirotkin, H.I. (2005) Chordin, FGF signaling, and mesodermal factors cooperate in zebrafish neural induction. Developmental Biology. 279(1):1-19
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