Genomic Feature
ut24Tg
Notes
| Comment | Citation |
|---|---|
| This line is a knock-in allele in which the EGFP cds has been inserted just ... | Troutwine et al., 2020 |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 24: 40171458 - 40171459 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- None
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| sspout24Tg/+ | Heterozygous | Unknown | Fig. 4  from Troutwine et al., 2020 | ||
| sspout24Tg | Unknown | Unknown | 2 figures from 2 publications | ||
| cfap298tm304/tm304; sspout24Tg | Complex | Figure 5. from Bearce et al., 2022 | Figure 5. from Bearce et al., 2022 | ||
| dnah10ut28/ut28; sspout24Tg/+ (AB) | Complex | Fig. 4 from Wang et al., 2021 | |||
| drukdut26Et/+; sspout24Tg/+ | Complex | Fig. 4 from Troutwine et al., 2020 | |||
| uts2r3b1436/b1436; sspout24Tg (AB) | Complex | Figure 5. from Bearce et al., 2022 | Figure 5. from Bearce et al., 2022 |
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Supplemental Information
- Genotyping protocol
- None
- Djebar, M., Anselme, I., Pezeron, G., Bardet, P.L., Cantaut-Belarif, Y., Eschstruth, A., López-Santos, D., Le Ribeuz, H., Jenett, A., Khoury, H., Veziers, J., Parmentier, C., Hirschler, A., Carapito, C., Bachmann-Gagescu, R., Schneider-Maunoury, S., Vesque, C. (2024) Astrogliosis and neuroinflammation underlie scoliosis upon cilia dysfunction. eLIFE. 13:
- Bearce, E.A., Irons, Z.H., O'Hara-Smith, J.R., Kuhns, C.J., Fisher, S.I., Crow, W.E., Grimes, D.T. (2022) Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology. eLIFE. 11:
- Wang, Y., Troutwine, B.R., Zhang, H., Gray, R.S. (2021) The axonemal dynein heavy chain 10 gene is essential for monocilia motility and spine alignment in zebrafish. Developmental Biology. 482:82-90
- Cantaut-Belarif, Y., Orts Del'Immagine, A., Penru, M., Pézeron, G., Wyart, C., Bardet, P.L. (2020) Adrenergic activation modulates the signal from the Reissner fiber to cerebrospinal fluid-contacting neurons during development. eLIFE. 9:
- Troutwine, B.R., Gontarz, P., Konjikusic, M.J., Minowa, R., Monstad-Rios, A., Sepich, D.S., Kwon, R.Y., Solnica-Krezel, L., Gray, R.S. (2020) The Reissner Fiber Is Highly Dynamic In Vivo and Controls Morphogenesis of the Spine. Current biology : CB. 30(12):2353-2362.e3
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