Genomic Feature
bns5
- ID
- ZDB-ALT-180503-6
- Name
- bns5
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Stainier Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 9: 40939499 - 40939508 (GRCz11) (1) Details
- Nucleotide change
- CAGCCTTCCA/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 10 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TGATATAACTACGAAAATGAGTACGGTTATTGTGTTATATGCGTAAATATAACATGTAGCCTTTGTCAGCTGCGTTTGACAAAAGACGCAAAGTGTGCACGCACGGAAATATGTATTTTAAATGTTTGTATTTTTCATAAATCTGCATAATTTCTCAGGTTCAAATGATTTCCCCACGAGTCCTCAAAGATGTGTTATACCTCTTTAAGAGCTGCGAAAGAAGTCCAGCTCTGTCCATTAGGTTTATTGTTGCCAGCTCAGCCAATCATTGAATCTTACGACACAATAGAGTGGCCAAAGTTGCAGTATAAAAAGCCTTGCCGAATTTAAGCATGACATCTACTTGTCCGGTGCGTGGTGAGGTTCATTTCCATAGCAAATCAGAACATCAAACATCCTTTAGCACGCCTTGGAACATGCATTTTACACAGGTTTTAATTTCTCTAAGTGTATTAATTGCATGTGGTCCAGTGGGTTATGGAGATATAACGGCGCACCAG
CAGCCTTCCA/- CAGCCACGGAGGAAAGCGAGCAGTGTTCCACATGTGAGTTCAGACAACACAGCAAGCTGATGAGACTGCATGCCATCAAGTCCCAAATTCTTAGCAAACTCCGACTCAAGCAGGCTCCAAACATCAGCCGGGACGTGGTCAAGCAGCTGTTACCCAAAGCACCGCCTTTGCAACAACTTCTGGATCAGTACGATGTTTTAGGAGATGACAGTAAGGATGGAGCTGTGGAAGAGGACGATGAACATGCCACCACAGAAACCATCATGACCATGGCCACAGAACGTAAGGATTATCTAGTTCAAAGATTAGTTCGCGTTAACGTATCCTCTTAATCTGGAGGTAGATACGGTACTTGGAGAGACCCTTTACGCAGTCTTAACGCTCGAGTCAGTAACACTCACAAGTCAACGATTGTGCATAAATGCACAATTCAGACACATTGTAGTTCTCCTTCCTGATTTAAAAAGGATATGGGTCGCTTCTTTATCAGTTTTGCCACA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| mstnbbns5/bns5 | Homozygous | ♀+/- ♂+/- | 7 figures  from 2 publications | Fig. 6 from Saraswathy et al., 2022 | |
| mstnbbns5/+ | Heterozygous | ♀+/- ♂+/- | Fig. 2 from Saraswathy et al., 2022 | ||
| mstnbbns5/bns5; hsc4Tg | Complex | Fig. 3 from Dogra et al., 2017 | |||
| mstnbbns5/bns5; hsc4Tg | Complex | Fig. S8 from Uribe et al., 2018 | |||
| mstnbbns5/bns5; nns11Tg | Complex |
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Supplemental Information
- Genotyping protocol
- None
- Cigliola, V., Shoffner, A., Lee, N., Ou, J., Gonzalez, T.J., Hoque, J., Becker, C.J., Han, Y., Shen, G., Faw, T.D., Abd-El-Barr, M.M., Varghese, S., Asokan, A., Poss, K.D. (2023) Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer. Nature communications. 14:48574857
- Saraswathy, V.M., Zhou, L., McAdow, A.R., Burris, B., Dogra, D., Reischauer, S., Mokalled, M.H. (2022) Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish. Cell Reports. 41:111705111705
- Uribe, V., Ramadass, R., Dogra, D., Rasouli, S.J., Gunawan, F., Nakajima, H., Chiba, A., Reischauer, S., Mochizuki, N., Stainier, D.Y.R. (2018) In vivo analysis of cardiomyocyte proliferation during trabeculation.. Development (Cambridge, England). 145(14):
- Dogra, D., Ahuja, S., Kim, H.T., Rasouli, S.J., Stainier, D.Y.R., Reischauer, S. (2017) Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair. Nature communications. 8:1902
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