Genomic Feature
hdb10Tg
- ID
- ZDB-ALT-180207-11
- Name
- hdb10Tg
- Synonyms
- None
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Maria Leptin Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 16: 41984294 - 41984295 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- None
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|---|---|
pycardhdb10Tg | Unknown | Unknown | Fig. 3 from Kuri et al., 2017 | 2 figures from Kuri et al., 2017 | |
pycardhdb10Tg; hdb2Tg | Complex | Fig. 2 from Kuri et al., 2017 |
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Supplemental Information
- Genotyping protocol
- None
- Shkarina, K., Hasel de Carvalho, E., Santos, J.C., Ramos, S., Leptin, M., Broz, P. (2022) Optogenetic activators of apoptosis, necroptosis, and pyroptosis. The Journal of cell biology. 221(6):
- Frame, J.M., Kubaczka, C., Long, T.L., Esain, V., Soto, R.A., Hachimi, M., Jing, R., Shwartz, A., Goessling, W., Daley, G.Q., North, T.E. (2020) Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Developmental Cell. 55(2):133-149.e6
- Li, Y., Huang, Y., Cao, X., Yin, X., Jin, X., Liu, S., Jiang, J., Jiang, W., Xiao, T.S., Zhou, R., Cai, G., Hu, B., Jin, T. (2018) Functional and Structural Characterization of Zebrafish ASC. The FEBS journal. 285(14):2691-2707
- Kuri, P., Schieber, N.L., Thumberger, T., Wittbrodt, J., Schwab, Y., Leptin, M. (2017) Dynamics of in vivo ASC speck formation. The Journal of cell biology. 216(9):2891-2909
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