Genomic Feature
sa6158
- ID
- ZDB-ALT-161003-18042
- Name
- sa6158
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation
- Protocol
- adult males treated with ENU
- Lab of Origin
- Stemple Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 10: 6896599 (GRCz11) (1) Details
- Nucleotide change
- T/A
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- T>A (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
GCGATTTCAACCAAAATAAGCAATTACACCCTATCAAACATATCTATAATAAGGAGCATGGTTGGTTACGGAGTTATTAACGCCACAAGACCAAACTAGGAAAGGATGGACTTTGAAGGAATAAACTATGGCAGGAAAGCTTCATTAAATTGCACTGAACAAGTTCTGGCCATGCATGCTCGAGGCAGGCAATTCCGTACAATTGCGTAATTTAGCAGCTTAAATTTATCGAGCTAATTATGACATCGGACCCATAACAATAAACTTAAAAGTAGCATTTATTGGCTGATAAACGATATGACCGTCTATATCTTGCATCCCTAAAATTAATCTATTTCTTTGACTACTGTTCAGGTTTTAGAGGCCGGAATGAGGAAGTATTTTCCAAGGGTAATTTACTGCATTTATATAAAATGTTCTAAAGTGTTAACTTTTTTTTTTATTATTATTTAATCCATTTTATTGTTTTCCTGTTTGTTCAGTCACAACTGCAGACAAGT
T/A GGATCAAGAAGGAAGTGAAAATGCAGGTGGGCAATATGTTATACATAAAGTAATCATCATGTTAAAATTGATTTAAGGAATTGGGGAGGAAGTAGAATTGATGGTCTTTAAACGAATTGTCTCGTAAATTGCTAAATTTTATACAAGAAGTGTTTTCCATAGTTTTTGGAGCTGACTTGCAAAAGATCAGATACAATTTAAGGACTGATTTAATACCAGACATTTTAATCATGGTGTTTGAGTCTTTTTGCTCTTAAATGACTGATATTAAAGAGGAGGAGAGAGTTGTAGTTTGAAGTGATAGATTTTCATCTGATAAAGTATTGCTTCAAGTAAATTGAATGGCCTTTTTTTTTTCAGGACCCAAGGTTGTTTATGTGCCGCCGCCTCCTCCAGAGGAGGAGAGCTCGATATTCTCCCATTATGCAACAGGCATTAATTTTGACAAATATGATGATATTCTTGTGGACGTGAGTGGCAGCAATCCTCCAAAAGCAATT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| ddx4sa6158/sa6158 | Homozygous | ♀+/- ♂+/- | 2 figures from Hartung et al., 2014 | 4 figures from Hartung et al., 2014 | |
| ddx4sa6158/+ | Heterozygous | Unknown | 4 figures from Hartung et al., 2014 | ||
| ddx4sa6158/sa6158; uc1Tg | Complex | 2 figures from Hartung et al., 2014 | 3 figures from Hartung et al., 2014 | ||
| ddx4sa6158/+; uc1Tg | Complex | 3 figures from Hartung et al., 2014 | |||
| ddx4sa6158/sa6158; tp53zdf1/zdf1 | Complex | Fig. 7 from Hartung et al., 2014 |
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Supplemental Information
- Genotyping protocol
- None
- Chen, Y., Lin, X., Dai, J., Bai, Y., Liu, F., Luo, D. (2024) Deletion of ddx4 Ovary-Specific Transcript Causes Dysfunction of Meiosis and Derepress of DNA Transposons in Zebrafish Ovaries. Biology. 13(12):
- Marinović, Z., Li, Q., Lujić, J., Iwasaki, Y., Csenki, Z., Urbányi, B., Yoshizaki, G., Horváth, Á. (2019) Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation. Scientific Reports. 9:13861
- Hartung, O., Forbes, M.M., Marlow, F.L. (2014) Zebrafish vasa is required for germ-cell differentiation and maintenance. Molecular reproduction and development. 81(10):946-61
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