Genomic Feature
sa1485
- ID
- ZDB-ALT-120411-534
- Name
- sa1485
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation
- Protocol
- adult males treated with ENU
- Lab of Origin
- Stemple Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 24: 1236274 (GRCz11) (1) Details
- Nucleotide change
- G/T
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- C>A (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
TCCTTCCCCGCTTTGAGCTGGAATCTTCCTGTTGGGCTGTTGGGTGTGTTTATGCAGCTCAAATACACACTAATATAAACTGCAATTACCTTGAGGAATGGAAGATTTTAGGTGTTATGACAACAGTCTACATTCCAGAGTCTTTCACCCCAATCTGCCCGAGACTAACCCATACTAACAGGAAAAAGTCTCAAATACTACCACAGACAATATTTCGAACTTGGACTGCAATACTTAGTTCAACCACTAGTCGTCAGCCCAACACATTGCACTGTTAAACTAAATAGTTACCAGATTCTTGTTGTCATATATGTTTGTGTTTCTGCACGTCTCTATATGAACATGATCCAACTATATGGCTGCTATTCTGTTAAAGTGTGCGCCTTTTAGAATTAATGTGCAAAAATCATCTGCTAAATGATTATTTTTTTCAGTTTAAGTATTCAGATTTTCTCCATTGACTCACCTCCAGGGAATCCGTCCCAAATCTCCAGGCGGTC
G/T TATCGGCAGAAGACTCCGGCGGGCGGCTGCGTGTCTGGCTCCAGCTCAAAACTCTCGAACTCTAAAACGATTTCTGACATCTTAGGAGCAAAGATCATGAACGTGCAGTCCAAATTATTGGGGTATTTCTCTGGAAATCCGGGCGACTTGATGACTCCGCTGCTGGAGGTGAAGTTCCTGGAACATTCTGGACCTACGGTGGACACAGAGAGGAAGGAAAAAGTGAGCTTTTTTGTTTGTTCACTCGGGCAGACGGAGTAAAGGGGAATAATAACAAACACTGAAGCAGAAACACGGTGGTCTGTGTTGTTTTGCTGGATGATTGCAGGGTTTATGGGCCGTGGTGGAGGCCCACCCTGCTCGGAATATGGCTGATGCTTGATTTTTTGGGGTGTGTTGTGGGCTAATGATGAAAATGAACCCAAAAAGAAAGCACAAGCGCATATGAGGCTGATCTTATTAAATGTTTTATATGCACTCGATGAAGTGACTGGTGCTTG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| nrp1asa1485/sa1485 | Homozygous | ♀+/- ♂+/- | |||
| nrp1asa1485/sa1485 | Homozygous | Unknown | 2 figures  from Lowe et al., 2019 | Fig. 3 from Lowe et al., 2019 | |
| nrp1asa1485/sa1485 (TL) | Homozygous | ♀+/- ♂+/- | text only from Busch-Nentwich et al., 2012 | ||
| nrp1asa1485/sa1485; li1Tg | Complex | Fig. 6 from Lowe et al., 2019 | |||
| nrp1asa1485/sa1485; p201Tg; p202Tg | Complex | 3 figures from Taku et al., 2016 | |||
| nrp1asa1485/sa1485; p201Tg; zf1062Tg | Complex | Fig. 8 from Dang et al., 2018 | Fig. 8 from Dang et al., 2018 | ||
| nrp1asa1485/sa1485; p201Tg; zf1063Tg | Complex | Fig. 8 from Dang et al., 2018 | |||
| nrp1asa1485/sa1485; y1Tg | Complex | Fig. 5 from Lowe et al., 2019 | |||
| dcctm272b/tm272b; nrp1asa1485/sa1485; p201Tg; p202Tg | Complex | Fig. 6 from Taku et al., 2016 | |||
| nrp1asa1485/sa1485; sema3dsa1661/sa1661; p201Tg; p202Tg | Complex | Fig. 5 from Taku et al., 2016 |
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Supplemental Information
- Genotyping protocol
- None
- Lowe, V., Wisniewski, L., Sayers, J., Evans, I., Frankel, P., Mercader-Huber, N., Zachary, I.C., Pellet-Many, C. (2019) Neuropilin 1 mediates epicardial activation and revascularization in the regenerating zebrafish heart. Development (Cambridge, England). 146(13):
- Dang, P., Fisher, S.A., Stefanik, D., Kim, J., Raper, J.A. (2018) Coordination of olfactory receptor choice with guidance receptor expression and function in olfactory sensory neurons. PLoS Genetics. 14:e1007164
- Taku, A.A., Marcaccio, C.L., Ye, W., Krause, G.J., Raper, J.A. (2016) Attractant and repellent cues cooperate in guiding a subset of olfactory sensory axons to a well-defined protoglomerular target. Development (Cambridge, England). 143:123-32
- Kok, F.O., Shin, M., Ni, C., Gupta, A., Grosse, A.S., van Impel, A., Kirchmaier, B.C., Peterson-Maduro, J., Kourkoulis, G., Male, I., DeSantis, D.F., Sheppard-Tindell, S., Ebarasi, L., Betsholtz, C., Schulte-Merker, S., Wolfe, S.A., Lawson, N.D. (2015) Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish. Developmental Cell. 32(1):97-108
- Dell, A.L., Fried-Cassorla, E., Xu, H., and Raper, J.A. (2013) cAMP-Induced Expression of Neuropilin1 Promotes Retinal Axon Crossing in the Zebrafish Optic Chiasm. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(27):11076-11088
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