Genomic Feature
zp3
- ID
- ZDB-ALT-060110-2
- Name
- zp3
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- ENU
- Lab of Origin
- Keating Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 1: 16393307 (GRCz11) (1) Details
- Nucleotide change
- T/G
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- A>C at position 443 (1)
- Transcript Consequence
- Missense (1)
- Protein Consequence
- Amino Acid Substitution: Tyr>Ser at position 148 (1)
- Flanking Sequence
-
CAGAAGCCTTCTAGAATTTTCAGTAGTAGTAAGAGATGTCTGTCATTCTCCCTCTTGTTTTATTTTAATCCAACCTCCCTTGGTGAATGGATCCAGATTATTGTTCTGTCTTTCAGGAACTATCCAGAGTCCGGATATGCCTGCTTCCTTCCACTCCAATCAAGGGCTTTCCATCTCCTGCATTTGCTCCAACATTGGACCTCAAATGAGGACCACTTTTCCCCCTCGCCTGCACTTCTTTCTCCAGAGAGCGCTCTGTCCGAGGGGGACATGCAGGTGCTTTTTGGGGTGGTTTTGAGTTTGAGGTTCATTGGTTTCAGCTGTGACCTAGAACATCCTTGTAAAGCTCAGGAACTCGCTCTGGATCCACAGGCCGCGGTAAGAAATGCGTGAAGCGCTGGTGTCTCCGGGAGCGTGCCCCATCTCTGGACGTCCCATCTTTGTTGAGGGCTACATAATAATGAGATCCACGCTCGCCATGCCGATACAGGTTAGAAGAG
T/G AAGTGTTGTACCAATTCTCCTCAAACTGCTCCCTGAACACACACTCGGCTGACAGCTTTTCCTAAGAGAGGCAGAGAAGGGGAGGCAAGGGTTAATCGCACTGCATAACAGAAGGATAAACTGTGTCCAAAGGCTATTTGAAATTGCACCATAAATCACATTCTCAATTTTAGCACGGGCGGGCTATGAATGAAATGAATTGTTGCATTACTCAAAATAAAATGTGGCTGGTGCAGTGCCGGAACCAAATGCATTTGTGCTATACTTACAGATCCGTACAGTTCGCCCTTGCTGTTCATTCCCAGATACAATCCGCTATCCACACCACGGATGCTCACCATCCCCACAGCGAGGCTAATGAATTCCAATATACCTGTGAGAAAAGCACAGCTGTTAGTTTCCAGTTGAGACAGCAGGACAAGCACCTGCAACAGTGGCATCAAACTGGCCTATACTTAATTCATGACGTCTTTCACACTTAATCACTGTGTTTTGCTATA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| fgf20azp3/zp3 | Homozygous | Unknown | 2 figures  from 2 publications | 3 figures from Whitehead et al., 2005 | |
| fgf20azp3/zp3 | Homozygous | ♀+/- ♂+/- | 4 figures from 4 publications | 4 figures from 4 publications | |
| fgf20azp3/zp3 (AB) | Homozygous | ♀+/- ♂+/- | 4 figures from Cooper et al., 2013 | ||
| fgf20azp3/zp3 (EKW) | Homozygous | ♀+/- ♂+/- | Fig. 5 from Kang et al., 2016 | Fig. 5 from Kang et al., 2016 | |
| fgf20azp3/+ (AB) | Heterozygous | Unknown | |||
| fgf20azp3/zp3; pd175Tg (EKW) | Complex | Fig. 5 from Kang et al., 2016 | |||
| fgf20azp3/zp3; pd176Tg (EKW) | Complex | Fig. 5 from Kang et al., 2016 | |||
| fgf20azp3/+; fgfr1at2227/+ | Complex | Fig. 4 from Daane et al., 2016 | |||
| fgf20azp3/+; fgfr1at2227/t2227 | Complex | Fig. 4 from Daane et al., 2016 | |||
| fgf20azp3/zp3; fgfr1at2227/+ | Complex | Fig. 4 from Daane et al., 2016 |
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Supplemental Information
- Genotyping protocol
- zp3.pdf
- Tseng, T.L., Wang, Y.T., Tsao, C.Y., Ke, Y.T., Lee, Y.C., Hsu, H.J., Poss, K.D., Chen, C.H. (2021) The RNA helicase Ddx52 functions as a growth switch in juvenile zebrafish. Development (Cambridge, England). 148(15):
- Tambalo, M., Mitter, R., Wilkinson, D.G. (2020) A single cell transcriptome atlas of the developing zebrafish hindbrain. Development (Cambridge, England). 147(6):
- König, D., Jaźwińska, A. (2019) Zebrafish fin regeneration involves transient serotonin synthesis. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 27(4):375-385
- Wang, Y.T., Tseng, T.L., Kuo, Y.C., Yu, J.K., Su, Y.H., Poss, K.D., Chen, C.H. (2019) Genetic Reprogramming of Positional Memory in a Regenerating Appendage. Current biology : CB. 29(24):4193-4207.e4
- König, D., Page, L., Chassot, B., Jaźwińska, A. (2017) Dynamics of actinotrichia regeneration in the adult zebrafish fin. Developmental Biology. 433(2):416-432
- Pfefferli, C., Jaźwińska, A. (2017) The careg element reveals a common regulation of regeneration in the zebrafish myocardium and fin. Nature communications. 8:15151
- Daane, J.M., Rohner, N., Konstantinidis, P., Djuranovic, S., Harris, M.P. (2016) Parallelism and epistasis in skeletal evolution identified through use of phylogenomic mapping strategies. Molecular Biology and Evolution. 33(1):162-73
- Kang, J., Hu, J., Karra, R., Dickson, A.L., Tornini, V.A., Nachtrab, G., Gemberling, M., Goldman, J.A., Black, B.L., Poss, K.D. (2016) Modulation of tissue repair by regeneration enhancer elements. Nature. 532(7598):201-6
- Chen, C.H., Merriman, A.F., Savage, J., Willer, J., Wahlig, T., Katsanis, N., Yin, V.P., Poss, K.D. (2015) Transient laminin beta 1a Induction Defines the Wound Epidermis during Zebrafish Fin Regeneration. PLoS Genetics. 11:e1005437
- Cooper, W.J., Wirgau, R.M., Sweet, E.M., and Albertson, R.C. (2013) Deficiency of zebrafish fgf20a results in aberrant skull remodeling that mimics both human cranial disease and evolutionarily important fish skull morphologies. Evolution & development. 15(6):426-441
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