Gene
prdx1
- ID
- ZDB-GENE-050320-35
- Name
- peroxiredoxin 1
- Symbol
- prdx1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have thioredoxin peroxidase activity. Involved in leukocyte activation. Localizes to protein-containing complex. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Is expressed in several structures, including diencephalon; digestive system; epidermis; lateral line; and neural crest. Orthologous to human PRDX1 (peroxiredoxin 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 26 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7148899 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Methylmalonic aciduria and homocystinuria, cblC type, digenic | 277400 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant | Peroxiredoxin, AhpC-type | Peroxiredoxin, C-terminal | Thioredoxin domain | Thioredoxin-like superfamily |
---|---|---|---|---|---|---|
UniProtKB:A2AWE1
|
199 |
Interactions and Pathways
No data available
Plasmids
No data available