FIGURE

Fig. 4

ID
ZDB-FIG-121116-49
Publication
Miller et al., 2012 - The alpha-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis
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Fig. 4

Early morphant malformations.

Images of embryo development from 6–18 hpf demonstrating early effects of TTP knockdown (right panel) compared to an injected control animal at the same age (left panel). Embryos from each MO injection type remain constant through 11 hpf. Beginning at 12 hpf, malformations are noticeable in the rostral region of the TRN embryo. These initial malformations occur in the head at the time the developing eye (marked) becomes distinguishable. The malformations in TRN embryos are more pronounced at later stages of development (16 and 18 hpf), while somite formation continues unabated. Images are frames from a time-lapse video (Videos S1 and S2).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage Range: 5-9 somites to 14-19 somites

Phenotype Detail
Acknowledgments
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