ZFIN ID: ZDB-LAB-970807-17
Hurley Lab
PI/Director: Hurley, James B.
Contact Person:
Email: sbrocker@u.washington.edu
URL: http://faculty.washington.edu/jbhhh/
Address: Department of Biochemistry University of Washington Box 357350 Seattle, WA 98195 USA
Country: United States
Phone: (206) 543-4222
Fax: (206) 685-2320
Line Designation: w


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 1 genomic features


STATEMENT OF RESEARCH INTERESTS
Vision in Zebrafish.


LAB MEMBERS
Van Epps, Heather Graduate Student Niemi, Gregory Research Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Giarmarco, M.M., Brock, D.C., Robbings, B.M., Cleghorn, W.M., Tsantilas, K.A., Kuch, K.C., Ge, W., Rutter, K.M., Parker, E.D., Hurley, J.B., Brockerhoff, S.E. (2020) Daily mitochondrial dynamics in cone photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. 117:28816-28827
Bisbach, C.M., Hutto, R.A., Poria, D., Cleghorn, W.M., Abbas, F., Vinberg, F., Kefalov, V.J., Hurley, J.B., Brockerhoff, S.E. (2020) Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria. Scientific Reports. 10:16041
Ward, R., Kaylor, J.J., Cobice, D.F., Pepe, D.A., McGarrigle, E.M., Brockerhoff, S.E., Hurley, J.B., Travis, G.H., Kennedy, B.N. (2020) Non-photopic and photopic visual cycles differentially regulate immediate, early and late-phases of cone photoreceptor-mediated vision. The Journal of biological chemistry. 295(19):6482-6497
Hutto, R.A., Bisbach, C.M., Abbas, F., Brock, D.C., Cleghorn, W.M., Parker, E.D., Bauer, B.H., Ge, W., Vinberg, F., Hurley, J.B., Brockerhoff, S.E. (2019) Increasing Ca2+ in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress. Cell death and differentiation. 27(3):1067-1085
Giarmarco, M.M., Cleghorn, W.M., Hurley, J.B., Brockerhoff, S.E. (2018) Preparing Fresh Retinal Slices from Adult Zebrafish for Ex Vivo Imaging Experiments. Journal of visualized experiments : JoVE. (135)
Kanow, M.A., Giarmarco, M.M., Jankowski, C.S., Tsantilas, K., Engel, A.L., Du, J., Linton, J.D., Farnsworth, C.C., Sloat, S.R., Rountree, A., Sweet, I.R., Lindsay, K.J., Parker, E.D., Brockerhoff, S.E., Sadilek, M., Chao, J.R., Hurley, J.B. (2017) Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye. eLIFE. 6
Giarmarco, M.M., Cleghorn, W.M., Sloat, S.R., Hurley, J.B., Brockerhoff, S.E. (2017) Mitochondria Maintain Distinct Ca2+ Pools in Cone Photoreceptors.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(8):2061-2072
Morrissey, M.E., Shelton, S., Brockerhoff, S.E., Hurley, J.B., and Kennedy, B.N. (2011) PRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptors. BMC Developmental Biology. 11:3
Kennedy, B.N., Alvarez, Y., Brockerhoff, S.E., Stearns, G.W., Sapetto-Rebow, B., Taylor, M.R., and Hurley, J.B. (2007) Identification of a Zebrafish Cone Photoreceptor-Specific Promoter and Genetic Rescue of Achromatopsia in the nof Mutant. Investigative ophthalmology & visual science. 48(2):522-529
Van Epps, H.A., Hayashi, M., Lucast, L., Stearns, G.W., Hurley, J.B., De Camilli, P., and Brockerhoff, S.E. (2004) The Zebrafish nrc Mutant Reveals a Role for the Polyphosphoinositide Phosphatase Synaptojanin 1 in Cone Photoreceptor Ribbon Anchoring. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(40):8641-8650
Kennedy, B.N., Stearns, G.W., Smyth, V.A., Ramamurthy, V., van Eeden, F., Ankoudinova, I., Raible, D., Hurley, J.B., and Brockerhoff, S.E. (2004) Zebrafish rx3 and mab21l2 are required during eye morphogenesis. Developmental Biology. 270(2):336-349
Taylor, M.R., Hurley, J.B., Van Epps, H.A., and Brockerhoff, S.E. (2004) A zebrafish model for pyruvate dehydrogenase deficiency: Rescue of neurological dysfunction and embryonic lethality using a ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America. 101(13):4584-4589
Kennedy, M.J., Dunn, F.A., and Hurley, J.B. (2004) Visual pigment phosphorylation but not transducin translocation can contribute to light adaptation in zebrafish cones. Neuron. 41(6):915-928
Brockerhoff, S.E., Rieke, F., Matthews, H.R., Taylor, M.R., Kennedy, B., Ankoudinova, I., Niemi, G.A., Tucker, C.L., Xiao, M., Cilluffo, M.C., Fain, G.L., and Hurley, J.B. (2003) Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and suppression of current in cones from the zebrafish mutant nof. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(2):470-480
Van Epps, H.A., Xiao, M., Ankoudinova, I.N., Hurley, J.B., and Brockerhoff, S.E. (2001) Photoreceptor synaptic transmission and light adaptation in the zebrafish visual mutant nrc. Investigative ophthalmology & visual science. 42(4):961
Van Epps, H.A., Yim, C.M., Hurley, J.B., and Brockerhoff, S.E. (2001) Investigations of photoreceptor synaptic transmission and light adaptation in the zebrafish visual mutant nrc. Investigative ophthalmology & visual science. 42(3):868-874
Taylor, M.R., Van Epps, H.A., Kennedy, M.J., Saari, J.C., Hurley, J.B., and Brockerhoff, S.E. (2000) Biochemical analysis of phototransduction and visual cycle in zebrafish larvae. Methods in enzymology. 316:536-557
Brockerhoff, S.E., Dowling, J.E., and Hurley, J.B. (1998) Zebrafish retinal mutants. Vision Research. 38:1335-1339
Brockerhoff, S.E., Hurley, J.B., Niemi, G.A., and Dowling, J.E. (1997) A new form of inherited red-blindness identified in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17(11):4236-4242
Brockerhoff, S.E., Hurley, J.B., Janssen-Bienhold, U., Neuhauss, S.C.F., Driever, W., and Dowling, J.E. (1995) A behavioral screen for isolating zebrafish mutants with visual system defects. Proceedings of the National Academy of Sciences of the United States of America. 92:10545-10549