ZFIN ID: ZDB-LAB-170214-6
Zhen-Yu Du Lab
PI/Director: Du, Zhen-Yu
Co-PI / Senior
Researcher:
Zhang, Mei-Ling
Contact Person: Li, Dong-Liang
Email: zydu@bio.ecnu.edu.cn
URL: http://laneh.ecnu.edu.cn/
Address: Laboratory of Aquaculture Nutrition and Environmental Health (LANEH) School of Life Sciences, East China Normal University 500 Dongchuan Road, Minhang District, Shanghai 200241, CHINA CHINA
Country: China
Phone: 86-21-54345354
Fax:
Line Designation: ecn


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 8 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Li, Dong-Liang Post-Doc Li, Jia-Min Graduate Student Limbu, Samwel Michele Graduate Student
Lu, Dong-Liang Graduate Student Wang, Jing Graduate Student Qiao, Fang Administrative Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Ma, Q., Luo, Y., Zhong, J., Limbu, S.M., Li, L.Y., Chen, L.Q., Qiao, F., Zhang, M.L., Lin, Q., Du, Z.Y. (2023) Hypoxia tolerance in fish depends on catabolic preference between lipids and carbohydrates. Zoological research. 44:954966954-966
Wang, J., Liu, C., Wang, S.P., Zhang, T.X., Chen, J.Y., Zhou, Q., Hou, Y., Yan, Z.G. (2023) BDE-209-induced genotoxicity, intestinal damage and intestinal microbiota dysbiosis in zebrafish (Danio Rerio). The Science of the total environment. 905:167009
Zhou, W.H., Luo, Y., Li, R.X., Degrace, P., Jourdan, T., Qiao, F., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2023) Inhibition of mitochondrial fatty acid β-oxidation activates mTORC1 pathway and protein synthesis via Gcn5-dependent acetylation of raptor in zebrafish. The Journal of biological chemistry. 299(10):105220
Sun, S.X., Liu, Y.C., Limbu, S.M., Li, D.L., Chen, L.Q., Zhang, M.L., Yin, Z., Du, Z.Y. (2023) Vitellogenin 1 is essential for fish reproduction by transporting DHA-containing phosphatidylcholine from liver to ovary. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1868(4):159289
Sun, S.X., Hu, C.T., Qiao, F., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2023) High dissolved oxygen exacerbates ammonia toxicity with sex-dependent manner in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 266:109549
Wang, J.G., Zhao, S.H., Qian, Y.C., Qian, Y.F., Liu, Y.C., Qiao, F., Luo, Y., Zhang, M.L., Du, Z.Y. (2022) The dysfunction of hormone-sensitive lipase induces lipid deposition and reprogramming of nutrient metabolism. The British journal of nutrition. 130(4):588-603
Wang, X., Ma, Q., Chen, L., Wu, H., Chen, L.Q., Qiao, F., Luo, Y., Zhang, M.L., Du, Z.Y. (2022) Peroxisome proliferator-activated receptor gamma is essential for stress adaptation by maintaining lipid homeostasis in female fish. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1867(7):159162
Wang, Z., Chen, W., Zuo, L., Xu, M., Wu, Y., Huang, J., Zhang, X., Li, Y., Wang, J., Chen, J., Wang, H., Sun, H. (2022) The Fibrillin-1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells. Cancer communications (London, England). 42(3):245-265
Shan, C., Li, M., Liu, Z., Xu, R., Qiao, F., Du, Z.Y., Zhang, M.L. (2021) Pediococcus pentosaceus Enhances Host Resistance Against Pathogen by Increasing IL-1β Production: Understanding Probiotic Effectiveness and Administration Duration. Frontiers in immunology. 12:766401
Qiao, F., Tan, F., Li, L.Y., Lv, H.B., Chen, L., Du, Z.Y., Zhang, M.L. (2021) Alteration and the Function of Intestinal Microbiota in High-Fat-Diet- or Genetics-Induced Lipid Accumulation. Frontiers in microbiology. 12:741616
Han, S.L., Qian, Y.C., Limbu, S.M., Wang, J., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2021) Lipolysis and lipophagy play individual and interactive roles in regulating triacylglycerol and cholesterol homeostasis and mitochondrial form in zebrafish. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1866(9):158988
Sun, S.X., Wu, J.L., Lv, H.B., Zhang, H.Y., Zhang, J., Limbu, S.M., Qiao, F., Chen, L.Q., Yang, Y., Zhang, M.L., Du, Z.Y. (2021) Corrigendum to: "Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways" [J. Hazard. Mater. 394 (2020) 122537]. Journal of hazardous materials. 406:124783
Han, S.L., Liu, Y., Limbu, S.M., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2020) The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish. Fish physiology and biochemistry. 47(1):173-188
Li, L.Y., Lv, H.B., Jiang, Z.Y., Qiao, F., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2020) Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish. The Journal of physiology. 598(20):4537-4553
Li, L.Y., Li, J.M., Ning, L.J., Lu, D.L., Luo, Y., Ma, Q., Limbu, S.M., Li, D.L., Chen, L.Q., Lodhi, I.J., Degrace, P., Zhang, M.L., Du, Z.Y. (2020) Mitochondrial Fatty Acid β-Oxidation Inhibition Promotes Glucose Utilization and Protein Deposition through Energy Homeostasis Remodeling in Fish. The Journal of nutrition. 150(9):2322-2335
Sun, S.X., Wu, J.L., Lv, H.B., Zhang, H.Y., Zhang, J., Limbu, S.M., Qiao, F., Chen, L.Q., Yang, Y., Zhang, M.L., Du, Z.Y. (2020) Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways. Journal of hazardous materials. 394:122537
Ma, Q., Hu, C.T., Yue, J., Luo, Y., Qiao, F., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) High-carbohydrate diet promotes the adaptation to acute hypoxia in zebrafish. Fish physiology and biochemistry. 46(2):665-679
Tan, F., Limbu, S.M., Qian, Y., Qiao, F., Du, Z.Y., Zhang, M. (2019) The Responses of Germ-Free Zebrafish (Danio rerio) to Varying Bacterial Concentrations, Colonization Time Points, and Exposure Duration. Frontiers in microbiology. 10:2156
Wang, J., Han, S.L., Lu, D.L., Li, L.Y., Limbu, S.M., Li, D.L., Zhang, M.L., Du, Z.Y. (2019) Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells. Frontiers in Physiology. 10:1077
Sun, S.X., Zhang, Y.N., Lu, D.L., Wang, W.L., Limbu, S.M., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) Concentration-dependent effects of 17β-estradiol and bisphenol A on lipid deposition, inflammation and antioxidant response in male zebrafish (Danio rerio). Chemosphere. 237:124422
Shi, C., Lu, Y., Zhai, G., Huang, J., Shang, G., Lou, Q., Li, D., Jin, X., He, J., Du, Z., Gui, J., Yin, Z. (2019) Hyperandrogenism in POMCa-deficient zebrafish enhances somatic growth without increasing adiposity. Journal of molecular cell biology. 12(4):291-304
Lu, D.L., Ma, Q., Sun, S.X., Zhang, H., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) Reduced oxidative stress increases acute cold stress tolerance in zebrafish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 235:166-173
Lu, D.L., Ma, Q., Wang, J., Li, L.Y., Han, S.L., Limbu, S.M., Li, D.L., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) Fasting enhances cold resistance in fish through stimulating lipid catabolism and autophagy. The Journal of physiology. 597(6):1585-1603
Sheng, Y., Ren, H., Limbu, S.M., Sun, Y., Qiao, F., Zhai, W., Du, Z.Y., Zhang, M. (2018) The Presence or Absence of Intestinal Microbiota Affects Lipid Deposition and Related Genes Expression in Zebrafish (Danio rerio).. Frontiers in microbiology. 9:1124
Li, J.M., Li, L.Y., Qin, X., Degrace, P., Demizieux, L., Limbu, S.M., Wang, X., Zhang, M.L., Li, D.L., Du, Z.Y. (2018) Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish. Frontiers in Physiology. 9:509
Zhou, L., Limbu, S.M., Qiao, F., Du, Z.Y., Zhang, M. (2018) Influence of Long-Term Feeding Antibiotics on the Gut Health of Zebrafish. Zebrafish. 15(4):340-348
Zhou, L., Limbu, S.M., Shen, M., Zhai, W., Qiao, F., He, A., Du, Z.Y., Zhang, M. (2017) Environmental concentrations of antibiotics impair zebrafish gut health. Environmental pollution (Barking, Essex : 1987). 235:245-254
Yang, B.Y., Zhai, G., Gong, Y.L., Su, J.Z., Peng, X.Y., Shang, G.H., Han, D., Jin, J.Y., Liu, H.K., Du, Z.Y., Yin, Z., Xie, S.Q. (2017) Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. American journal of physiology. Endocrinology and metabolism. 315(1):E38-E51
Peng, X., Shang, G., Wang, W., Chen, X., Lou, Q., Zhai, G., Li, D., Du, Z., Ye, Y., Jin, X., He, J., Zhang, Y., Yin, Z. (2017) Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)2D3.. Cell Reports. 19:1444-1455
Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Corrigendum: Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:44970
Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:40815
Liu, H.J., Zhang, C.Y., Song, F., Xiao, T., Meng, J., Zhang, Q., Liang, C.L., Li, S., Wang, J., Zhang, B., Liu, Y.R., Sun, T., Zhou, H.G. (2015) A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor γ with Excellent Effect on Insulin Resistance and Type 2 Diabetes. The Journal of pharmacology and experimental therapeutics. 353:573-81