ZFIN ID: ZDB-LAB-140613-2
Rossi Lab
PI/Director: Rossi, Adriano
Contact Person: Rossi, Adriano
Email: a.g.rossi@ed.ac.uk
URL:
Address: MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ
Country: France
Phone: +44 131 242 6659
Fax:
Line Designation: ed


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 1 genomic features


STATEMENT OF RESEARCH INTERESTS
Role of neutrophil apoptosis and cyclin-dependent kinases in resolution of inflammation


LAB MEMBERS
Hoodless, Laura Graduate Student Duffin, Rodger Lucas, Chris


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Rinaldi, G., Álvarez de Haro, N., Fernando, A.J., Desbois, A.P., Robb, C.T., Rossi, A.G. (2023) Fish Erythrocyte Extracellular Traps (FEETs) are an evolutionary conserved cellular process triggered by different stimuli. Fish & shellfish immunology. 136:108638
Gillies, S., Verdon, R., Stone, V., Brown, D.M., Henry, T., Tran, L., Tucker, C., Rossi, A.G., Tyler, C.R., Johnston, H.J. (2022) Transgenic zebrafish larvae as a non-rodent alternative model to assess pro-inflammatory (neutrophil) responses to nanomaterials. Nanotoxicology. 16(3):333-354
Bruton, F.A., Kaveh, A., Ross-Stewart, K.M., Matrone, G., Oremek, M.E.M., Solomonidis, E.G., Tucker, C.S., Mullins, J.J., Lucas, C.D., Brittan, M., Taylor, J.M., Rossi, A.G., Denvir, M.A. (2022) Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration. Developmental Cell. 57(12):1512-1528.e5
Lucas, C.D., Medina, C.B., Bruton, F.A., Dorward, D.A., Raymond, M.H., Tufan, T., Etchegaray, J.I., Barron, B., Oremek, M.E.M., Arandjelovic, S., Farber, E., Onngut-Gumuscu, S., Ke, E., Whyte, M.K.B., Rossi, A.G., Ravichandran, K.S. (2022) Pannexin 1 drives efficient epithelial repair after tissue injury. Science immunology. 7:eabm4032
Xiao, Y., Petrucco, L., Hoodless, L.J., Portugues, R., Czopka, T. (2022) Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling. Nature Neuroscience. 25(3):280-284
Kaveh, A., Bruton, F.A., Oremek, M.E.M., Tucker, C.S., Taylor, J.M., Mullins, J.J., Rossi, A.G., Denvir, M.A. (2021) Selective CDK9 inhibition resolves neutrophilic inflammation and enhances cardiac regeneration in larval zebrafish. Development (Cambridge, England). 149(8):
Siems, S.B., Jahn, O., Hoodless, L.J., Jung, R.B., Hesse, D., Möbius, W., Czopka, T., Werner, H.B. (2021) Proteome Profile of Myelin in the Zebrafish Brain. Frontiers in cell and developmental biology. 9:640169
Kaveh, A., Bruton, F.A., Buckley, C., Oremek, M.E.M., Tucker, C.S., Mullins, J.J., Taylor, J.M., Rossi, A.G., Denvir, M.A. (2020) Live Imaging of Heart Injury in Larval Zebrafish Reveals a Multi-Stage Model of Neutrophil and Macrophage Migration. Frontiers in cell and developmental biology. 8:579943
Marisca, R., Hoche, T., Agirre, E., Hoodless, L.J., Barkey, W., Auer, F., Castelo-Branco, G., Czopka, T. (2020) Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation. Nature Neuroscience. 23(3):363-374
Taylor, J.M., Nelson, C.J., Bruton, F.A., Baghbadrani, A.K., Buckley, C., Tucker, C.S., Rossi, A.G., Mullins, J.J., Denvir, M.A. (2019) Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart. Nature communications. 10:5173
Johnston, H.J., Verdon, R., Gillies, S., Brown, D.M., Fernandes, T.F., Henry, T.B., Rossi, A.G., Tran, L., Tucker, C., Tyler, C.R., Stone, V. (2017) Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials. Critical reviews in toxicology. 48(3):252-271
Hoodless, L.J., Lucas, C.D., Duffin, R., Denvir, M.A., Haslett, C., Tucker, C.S., Rossi, A.G. (2016) Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo. Scientific Reports. 5:36980
Hoodless, L.J., Robb, C.T., Felton, J.M., Tucker, C.S., Rossi, A.G. (2016) Models for the Study of the Cross Talk Between Inflammation and Cell Cycle. Methods in molecular biology (Clifton, N.J.). 1336:179-209
Lucas, C.D., Hoodless, L.J., Rossi, A.G. (2014) Swimming against the tide: drugs drive neutrophil reverse migration. Science Translational Medicine. 6:225fs9
Lucas, C.D., Allen, K.C., Dorward, D.A., Hoodless, L.J., Melrose, L.A., Marwick, J.A., Tucker, C.S., Haslett, C., Duffin, R., and Rossi, A.G. (2013) Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 27(3):1084-1094