Jing et al., 2020 - Synthetic lethal targeting of TET2-mutant hematopoietic stem and progenitor cells (HSPCs) with TOP1-targeted drugs and PARP1 inhibitors. Leukemia   34(11):2992-3006 Full text @ Leukemia
4 Genes / Markers
Marker Type Symbol Name
Gene myb v-myb avian myeloblastosis viral oncogene homolog
Gene parp1 poly (ADP-ribose) polymerase 1
Gene tdp1 tyrosyl-DNA phosphodiesterase 1
Gene tet2 tet methylcytosine dioxygenase 2