Gene
per2
- ID
- ZDB-GENE-011220-2
- Name
- period circadian clock 2
- Symbol
- per2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits chromatin binding activity. Involved in several processes, including circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and locomotor rhythm. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome and advanced sleep phase syndrome 1. Is expressed in heart; liver; muscle; nervous system; and ovary. Orthologous to human PER2 (period circadian regulator 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 34 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| advanced sleep phase syndrome 1 | Alliance | ?Advanced sleep phase syndrome, familial, 1 | 604348 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PAS domain | PAS domain superfamily | PAS fold-3 | Period circadian-like, C-terminal | Period circadian protein homolog 1-3, PAS-A domain |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QUT1
|
1399 | |||||
|
UniProtKB:A0A8M9PS01
|
1417 | |||||
|
UniProtKB:A0A8M9QFB2
|
1418 |
Interactions and Pathways
No data available
Plasmids
No data available