CRISPR

CRISPR4-mcu

ID
ZDB-CRISPR-200511-1
Name
CRISPR4-mcu
Previous Names
None
Target
Sequence
5' - GTCTTTGAACCTGCCATGAGGGG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
sh214 mcu
Expression
Gene expression in Wild Types + CRISPR4-mcu
No data available
Phenotype
Phenotype resulting from CRISPR4-mcu
No data available
Phenotype of all Fish created by or utilizing CRISPR4-mcu
Phenotype Fish Conditions Figures
liver mcu expression decreased amount, abnormal mcush214/sh214 (AB) standard conditions Fig. 1. with image from Soman et al., 2019
head mcu expression decreased amount, abnormal mcush214/sh214 (AB) standard conditions Fig. 1. with image from Soman et al., 2019
brain mcu expression decreased amount, abnormal mcush214/sh214 (AB) standard conditions Fig. 1. with image from Soman et al., 2019
whole organism mcu expression decreased amount, abnormal mcush214/sh214 (AB) standard conditions Fig. 1. with image from Soman et al., 2019
calcium import into the mitochondrion decreased occurrence, abnormal mcush214/sh214 (AB) standard conditions Fig. 1. with image from Soman et al., 2019
diencephalon has number of dopaminergic neuron, ameliorated mcush214/sh214 (AB) chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Fig. 6. with image from Soman et al., 2019
regulation of mitochondrial membrane potential process quality, ameliorated pink1sh397/sh397; mcush214/sh214 (AB) standard conditions Fig. 4 with image from Soman et al., 2019
dopaminergic neuron mitochondrion area, ameliorated pink1sh397/sh397; mcush214/sh214 (AB) standard conditions Fig. 5. with image from Soman et al., 2019
diencephalon has number of dopaminergic neuron, ameliorated pink1sh397/sh397; mcush214/sh214 (AB) standard conditions Fig. 3. with imageFig. 6. with image from Soman et al., 2019
calcium import into the mitochondrion decreased occurrence, exacerbated pink1sh397/sh397; mcush214/sh214 (AB) standard conditions Fig. 2. with image from Soman et al., 2019
diencephalon has number of dopaminergic neuron, ameliorated pink1sh397/sh397; mcush214/sh214 (AB) chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Fig. 6. with image from Soman et al., 2019
skeletal muscle cell mitochondrion morphology, ameliorated pink1sh397/sh397; mcush214/sh214; cms1Tg (AB) standard conditions Fig. 5. with image from Soman et al., 2019
skeletal muscle cell mitochondrion decreased volume, abnormal pink1sh397/sh397; mcush214/sh214; cms1Tg (AB) standard conditions Fig. 5. with image from Soman et al., 2019
Citations