CRISPR

CRISPR1-rabl3

ID

ZDB-CRISPR-200227-1

Name

CRISPR1-rabl3

Previous Names

None

Target

rabl3 (1)

Sequence

5' - GGGGAATCCCTCATGGACTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3183	rabl3
zf3184	rabl3

Expression

Gene expression in Wild Types + CRISPR1-rabl3

No data available

Phenotype

Phenotype resulting from CRISPR1-rabl3

No data available

Phenotype of all Fish created by or utilizing CRISPR1-rabl3

Phenotype	Fish	Conditions	Figures
cartilage tissue increased amount, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
rib morphology, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
vertebral column curved, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
whole organism decreased length, ameliorated	rabl3^{zf3183/zf3183}	chemical treatment by environment: trametinib	Fig. 4 from Nissim et al., 2019
cranium morphology, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
vertebral column decreased thickness, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
bone tissue mineralized, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
cranial vault decreased thickness, ameliorated	rabl3^{zf3183/zf3183}	chemical treatment by environment: trametinib	Fig. 4 from Nissim et al., 2019
vertebral column decreased thickness, ameliorated	rabl3^{zf3183/zf3183}	chemical treatment by environment: trametinib	Fig. 4 from Nissim et al., 2019
cranial vault decreased thickness, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
whole organism decreased length, abnormal	rabl3^{zf3183/zf3183}	standard conditions	Fig. 4 from Nissim et al., 2019
peripheral nervous system neurofibrosarcoma increased amount, exacerbated	rabl3^zf3183/+	chemical treatment by environment: 7,12-dimethyltetraphene	Fig. 2 from Nissim et al., 2019
peripheral nervous system neurofibrosarcoma increased amount, exacerbated	tp53^zdf1/zdf1; rabl3^zf3184/+	standard conditions	Fig. 2 from Nissim et al., 2019

Citations