TALEN

TALEN2-nanog

ID
ZDB-TALEN-180423-1
Name
TALEN2-nanog
Previous Names
None
Target
Target Sequence 1
5' - TTTAACCCATCTTATC - 3'
Target Sequence 2
5' - TGCGGGTACATGAGCC - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
m1435 nanog
Expression
Gene expression in Wild Types + TALEN2-nanog
No data available
Phenotype
Phenotype resulting from TALEN2-nanog
No data available
Phenotype of all Fish created by or utilizing TALEN2-nanog
Phenotype Fish Conditions Figures
endoderm sox17 expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
yolk microtubule structure, abnormal nanogm1435/m1435 standard conditions Fig. 4 with image from Veil et al., 2017
yolk syncytial layer morphology, abnormal nanogm1435/m1435 standard conditions Fig. 4 with image from Veil et al., 2017
whole organism ventral region vent expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 7 with image from Veil et al., 2017
epiblast bmp2b expression absent, abnormal nanogm1435/m1435 standard conditions Fig. 7 with image from Veil et al., 2017
whole organism morphology, abnormal nanogm1435/m1435 standard conditions Fig. 1 with image from Veil et al., 2017
presumptive endoderm sox32 expression absent, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
shield increased size, abnormal nanogm1435/m1435 standard conditions Fig. 1 with image from Veil et al., 2017
presumptive endoderm gata5 expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
epiboly delayed, abnormal nanogm1435/m1435 standard conditions Fig. 1 with image from Veil et al., 2017
yolk syncytial layer mxtx2 expression absent, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
blastoderm detached from yolk, abnormal nanogm1435/m1435 standard conditions Fig. 1 with image from Veil et al., 2017
whole organism her3 expression increased amount, abnormal nanogm1435/m1435 standard conditions Fig. 7 with image from Veil et al., 2017
presumptive endoderm mixl1 expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
whole organism ventral region vox expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 7 with image from Veil et al., 2017
embryo development arrested, abnormal nanogm1435/m1435 standard conditions Fig. 1 with image from Veil et al., 2017
epiblast vox expression absent, abnormal nanogm1435/m1435 standard conditions Fig. 7 with image from Veil et al., 2017
presumptive endoderm sox32 expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
endoderm sox17 expression decreased distribution, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
chromatin remodeling disrupted, abnormal nanogm1435/m1435 standard conditions Fig 4 with image from Pálfy et al., 2020
presumptive mesoderm foxd3 expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
whole organism eomesa expression increased amount, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
presumptive mesoderm tbxta expression decreased amount, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
presumptive endoderm mixl1 expression absent, abnormal nanogm1435/m1435 standard conditions Fig. 3 with image from Veil et al., 2017
DEL her3 expression increased amount, abnormal nanogm1435/m1435 standard conditions Fig. 7 with image from Veil et al., 2017
yolk structure, abnormal nanogm1435/m1435 standard conditions Fig. 1 with image from Veil et al., 2017
yolk syncytial layer actin filament structure, abnormal nanogm1435/m1435 standard conditions Fig. 4 with image from Veil et al., 2017
yolk syncytial layer cell position, abnormal nanogm1435/m1435 standard conditions Fig. 4 with image from Veil et al., 2017
endoderm sox17 expression decreased amount, abnormal nanogm1435 standard conditions Fig. 3 with image from Veil et al., 2017
cell death increased occurrence, abnormal nanogm1435 standard conditions Fig. 2 with image from Veil et al., 2017
whole organism morphology, abnormal nanogm1435 standard conditions Fig. 1 with image from Veil et al., 2017
epiboly delayed, abnormal nanogm1435 standard conditions Fig. 1 with image from Veil et al., 2017
yolk syncytial layer mxtx2 expression absent, abnormal nanogm1435 standard conditions Fig. 3 with image from Veil et al., 2017
endoderm sox17 expression decreased distribution, abnormal nanogm1435 standard conditions Fig. 3 with image from Veil et al., 2017
whole organism decreased length, abnormal nanogm1435 standard conditions Fig. 1 with image from Veil et al., 2017
Citations