Gene
slc16a2
- ID
- ZDB-GENE-120117-1
- Name
- solute carrier family 16 member 2
- Symbol
- slc16a2 Nomenclature History
- Previous Names
-
- MCT8 (1)
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Exhibits thyroid hormone binding activity. Involved in several processes, including chordate embryonic development; nervous system development; and thyroid gland development. Predicted to localize to integral component of plasma membrane. Used to study Allan-Herndon-Dudley syndrome. Human ortholog(s) of this gene implicated in Allan-Herndon-Dudley syndrome and intellectual disability. Is expressed in several structures, including cardiovascular system; central nervous system; digestive system; eye; and hindbrain neural keel. Orthologous to human SLC16A2 (solute carrier family 16 member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 34 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Allan-Herndon-Dudley syndrome | Alliance | Allan-Herndon-Dudley syndrome | 300523 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Major facilitator superfamily | Major facilitator superfamily domain | MFS transporter superfamily |
|---|---|---|---|---|
|
UniProtKB:G8XYX6
|
526 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance