Gene
siah2l
- ID
- ZDB-GENE-030922-1
- Name
- seven in absentia homolog 2 (Drosophila)-like
- Symbol
- siah2l Nomenclature History
- Previous Names
-
- siaz (1)
- zgc:66284
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of circadian rhythm. Predicted to localize to cytoplasm. Is expressed in dorsal aorta; gut; male organism; nervous system; and otic vesicle. Orthologous to human SIAH2 (siah E3 ubiquitin protein ligase 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66284 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001841 | Zinc finger, RING-type |
Domain | IPR013010 | Zinc finger, SIAH-type |
Domain | IPR018121 | Seven-in-absentia protein, TRAF-like domain |
Family | IPR004162 | E3 ubiquitin-protein ligase SINA-like, animal |
Homologous_superfamily | IPR008974 | TRAF-like |
Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
Protein | Length | E3 ubiquitin-protein ligase SINA-like, animal | Seven-in-absentia protein, TRAF-like domain | TRAF-like | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, SIAH-type |
---|---|---|---|---|---|---|---|
UniProtKB:G8JL17
|
330 | ||||||
UniProtKB:Q7SYL3
|
331 | ||||||
UniProtKB:A0A8M2BHM7
|
231 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
siah2l-201
(1)
|
1787 nt |
Interactions and Pathways
No data available
Plasmids
No data available