ZFIN Person: Gawel, Kinga Aurelia

ZFIN ID: ZDB-PERS-201202-2

Gawel, Kinga Aurelia

Email:	kingagawel@o2.pl
URL:
Affiliation:	Gawel Lab
Address:	Department of Experimental and Clinical Pharmacology Medical University of Lublin Jaczewskiego 8b, 20-090 Lublin, Poland kingagawel@umlub.pl
Country:	Poland
Phone:	+48 81 448 6460
Fax:
ORCID ID:	0000-0001-8857-847X

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Nieoczym, D., Marszalek-Grabska, M., Szalak, R., Kundap, U., Kaczor, A.A., Wrobel, T.M., Kosheva, N., Komar, M., Abram, M., Esguerra, C.V., Samarut, E., Pieróg, M., Jakubiec, M., Kaminski, K., Kukula-Koch, W., Gawel, K. (2024) A comprehensive assessment of palmatine as anticonvulsant agent - In vivo and in silico studies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 172:116234116234

Grabarska, A., Luszczki, J.J., Gawel, K., Kukula-Koch, W., Juszczak, M., Slawinska-Brych, A., Adamczuk, G., Dmoszynska-Graniczka, M., Kosheva, N., Rzeski, W., Stepulak, A. (2023) Heterogeneous Cellular Response of Primary and Metastatic Human Gastric Adenocarcinoma Cell Lines to Magnoflorine and Its Additive Interaction with Docetaxel. International Journal of Molecular Sciences. 24(21):

Marszalek-Grabska, M., Gawel, K., Kosheva, N., Kocki, T., Turski, W.A. (2023) Developmental Exposure to Kynurenine Affects Zebrafish and Rat Behavior. Cells. 12(18):

Stępnik, K., Kukula-Koch, W., Plazinski, W., Rybicka, M., Gawel, K. (2023) Neuroprotective Properties of Oleanolic Acid-Computational-Driven Molecular Research Combined with In Vitro and In Vivo Experiments. Pharmaceuticals (Basel, Switzerland). 16(9):

Knap, B., Nieoczym, D., Kundap, U., Kusio-Targonska, K., Kukula-Koch, W., Turski, W.A., Gawel, K. (2023) Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties-a review. Frontiers in molecular neuroscience. 16:12216651221665

Nieoczym, D., Banono, N.S., Stępnik, K., Kaczor, A.A., Szybkowski, P., Esguerra, C.V., Kukula-Koch, W., Gawel, K. (2023) In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice. International Journal of Molecular Sciences. 24(16):

Stępnik, K., Kukula-Koch, W., Plazinski, W., Gawel, K., Gaweł-Bęben, K., Khurelbat, D., Boguszewska-Czubara, A. (2023) Significance of Astragaloside IV from the Roots of Astragalus mongholicus as an Acetylcholinesterase Inhibitor-From the Computational and Biomimetic Analyses to the In Vitro and In Vivo Studies of Safety. International Journal of Molecular Sciences. 24(11):

Doboszewska, U., Socała, K., Pieróg, M., Nieoczym, D., Sawicki, J., Szafarz, M., Gawel, K., Rafało-Ulińska, A., Sajnóg, A., Wyska, E., Esguerra, C.V., Szewczyk, B., Maćkowiak, M., Barałkiewicz, D., Mlyniec, K., Nowak, G., Sowa, I., Wlaź, P. (2023) TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice. Cellular and molecular life sciences : CMLS. 80:133133

Nakonieczna, S., Grabarska, A., Gawel, K., Wróblewska-Łuczka, P., Czerwonka, A., Stepulak, A., Kukula-Koch, W. (2022) Isoquinoline Alkaloids from Coptis chinensis Franch: Focus on Coptisine as a Potential Therapeutic Candidate against Gastric Cancer Cells. International Journal of Molecular Sciences. 23(18)

Silvennoinen, K., Gawel, K., Tsortouktzidis, D., Pitsch, J., Alhusaini, S., van Loo, K.M.J., Picardo, R., Michalak, Z., Pagni, S., Martins Custodio, H., Mills, J., Whelan, C.D., de Zubicaray, G.I., McMahon, K.L., van der Ent, W., Kirstein-Smardzewska, K.J., Tiraboschi, E., Mudge, J.M., Frankish, A., Thom, M., Wright, M.J., Thompson, P.M., Schoch, S., Becker, A.J., Esguerra, C.V., Sisodiya, S.M. (2022) SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility. Acta Neuropathologica. 144(1):107-127

Gawel, K., Kukula-Koch, W., Banono, N.S., Nieoczym, D., Targowska-Duda, K.M., Czernicka, L., Parada-Turska, J., Esguerra, C.V. (2021) 6-Gingerol, a Major Constituent of Zingiber officinale Rhizoma, Exerts Anticonvulsant Activity in the Pentylenetetrazole-Induced Seizure Model in Larval Zebrafish. International Journal of Molecular Sciences. 22(14):

Banono, N.S., Gawel, K., De Witte, L., Esguerra, C.V. (2020) Zebrafish Larvae Carrying a Splice Variant Mutation in cacna1d: A New Model for Schizophrenia-Like Behaviours?. Molecular neurobiology. 58(2):877-894

Gawel, K., Langlois, M., Martins, T., van der Ent, W., Tiraboschi, E., Jacmin, M., Crawford, A.D., Esguerra, C.V. (2020) Seizing the moment: Zebrafish epilepsy models. Neuroscience and biobehavioral reviews. 116:1-20

Gawel, K., Kukula-Koch, W., Nieoczym, D., Stepnik, K., Ent, W.V., Banono, N.S., Tarabasz, D., Turski, W.A., Esguerra, C.V. (2020) The Influence of Palmatine Isolated from Berberis sibiricaRadix on Pentylenetetrazole-Induced Seizures in Zebrafish. Cells. 9(5):

Tiraboschi, E., Martina, S., van der Ent, W., Grzyb, K., Gawel, K., Cordero-Maldonado, M.L., Poovathingal, S.K., Heintz, S., Satheesh, S.V., Brattespe, J., Xu, J., Suster, M., Skupin, A., Esguerra, C.V. (2020) New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome. Epilepsia. 61(3):549-560

Gawel, K., Turski, W.A., van der Ent, W., Mathai, B.J., Kirstein-Smardzewska, K.J., Simonsen, A., Esguerra, C.V. (2019) Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene. Molecular neurobiology. 57(4):1904-1916

Kamiński, K., Socała, K., Zagaja, M., Andres-Mach, M., Abram, M., Jakubiec, M., Pieróg, M., Nieoczym, D., Rapacz, A., Gawel, K., Esguerra, C.V., Latacz, G., Lubelska, A., Szulczyk, B., Szewczyk, A., Łuszczki, J.J., Wlaź, P. (2019) N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 17(1):309-328

Gawel, K., Banono, N.S., Michalak, A., Esguerra, C.V. (2019) A critical review of zebrafish schizophrenia models: time for validation?. Neuroscience and biobehavioral reviews. 107:6-22

Nieoczym, D., Socała, K., Gawel, K., Esguerra, C.V., Wyska, E., Wlaź, P. (2019) Anticonvulsant Activity of Pterostilbene in Zebrafish and Mouse Acute Seizure Tests. Neurochemical research. 44(5):1043-1055

NON-ZEBRAFISH PUBLICATIONS