ZFIN Human Disease: craniosynostosis

OBO ID: DOID:2340

Term Name:	craniosynostosis		Search Ontology:
Synonyms:	Premature closure of cranial sutures
Definition:	A synostosis that results_in premature fusion located_in skull. (4)
References:	GARD:6209 ICD10CM:Q75.0 MESH:D003398 NCI:C84655 OMIM:123100 OMIM:182212 OMIM:600593 OMIM:600775 OMIM:604757 OMIM:615314 ORDO:1531 SNOMEDCT_US_2023_03_01:205414007 UMLS_CUI:C0010278
Ontology:	Human Disease ( DOID:2340 )

Relationships

is a type of:	synostosis synostosis Show first 5 Terms
has subtype:	Antley-Bixler syndrome craniosynostosis 7 Crouzon syndrome Muenke Syndrome Antley-Bixler syndrome craniosynostosis 7 Crouzon syndrome Muenke Syndrome Show first 5 Terms

OTHER craniosynostosis PAGES

Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
ERF	erf	Craniosynostosis 4	600775
MSX2	msx2b msx2a	Craniosynostosis 2	604757
SKI	skia skib	Shprintzen-Goldberg syndrome	182212
TCF12	tcf12	Craniosynostosis 3	615314
TWIST1	twist1b twist1a	Craniosynostosis 1	123100

ZEBRAFISH MODELS

Fish	Conditions	Citations
WT	chemical treatment: talarozole	Laue et al., 2011
cyp26b1^{t24295/t24295}	standard conditions	Laue et al., 2011
WT + MO1-skib	standard conditions	Doyle et al., 2012
WT + MO2-skia	standard conditions	Doyle et al., 2012

PHENOTYPE No data available

CITATIONS (4)