ZFIN Human Disease: Smith-Lemli-Opitz syndrome

OBO ID: DOID:14692

Term Name:	Smith-Lemli-Opitz syndrome		Search Ontology:
Synonyms:	Rutledge lethal multiple congenital anomaly syndrome Smith-Opitz-Inborn syndrome
Definition:
References:	GARD:5683 ICD10CM:E78.72 MESH:D019082 NCI:C85071 OMIM:270400 SNOMEDCT_US_2023_03_01:43929004 UMLS_CUI:C0175694
Ontology:	Human Disease ( DOID:14692 )

Relationships

is a type of:	lipid metabolism disorder lipid metabolism disorder Show first 5 Terms

OTHER Smith-Lemli-Opitz syndrome PAGES

Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
DHCR7	dhcr7	Smith-Lemli-Opitz syndrome	270400

ZEBRAFISH MODELS

Fish	Conditions	Citations
AB/TL	chemical treatment: N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine	Cook et al., 2020
	chemical treatment: trazodone	Cook et al., 2020
AB/TL + MO1-dhcr7	control	Cook et al., 2020

PHENOTYPE No data available

CITATIONS (1)