ZFIN Human Disease: Parkinson's disease

OBO ID: DOID:14330

OBO ID: DOID:14330

Term Name:	Parkinson's disease	Search Ontology:
Synonyms:	paralysis agitans Parkinson disease
Definition:	A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions. (3)
References:	GARD:10251 ICD10CM:G20 ICD9CM:332 KEGG:05012 MESH:D010300 NCI:C26845 OMIM:PS168600 ORDO:2828 SNOMEDCT_US_2023_03_01:49049000 UMLS_CUI:C0030567
Ontology:	Human Disease ( DOID:14330 )

Relationships

is a type of:	synucleinopathy synucleinopathy Show first 5 Terms
has subtype:	early-onset Parkinson's disease late onset Parkinson's disease early-onset Parkinson's disease late onset Parkinson's disease Show first 5 Terms

OTHER Parkinson's disease PAGES

Alliance (1)

GENES INVOLVED No data available

ZEBRAFISH MODELS

Fish	Conditions	Citations
AB	chemical treatment: oxidopamine	Feng et al., 2014
	chemical treatment by environment: oxidopamine	Cronin et al., 2017
	chemical treatment by environment: oxidopamine	Zhang et al., 2011
	chemical treatment by environment: oxidopamine	Feng et al., 2020
	chemical treatment by environment: oxidopamine	Feng et al., 2019
	chemical treatment by environment: oxidopamine	Sun et al., 2020
	chemical treatment by environment: oxidopamine	Yu et al., 2021
	chemical treatment by environment: oxidopamine	Kozioł et al., 2020
	chemical treatment by environment: 6-hydroxy-L-dopa	Benvenutti et al., 2018
	chemical treatment by environment: oxidopamine	Kesh et al., 2020
	chemical treatment by environment: oxidopamine	Li et al., 2018
	chemical treatment by injection: oxidopamine	Matsui et al., 2017
	chemical treatment: oxidopamine	Zhang et al., 2017
	chemical treatment by environment: N-methyl-4-phenylpyridinium	Dukes et al., 2016
	chemical treatment by environment: N-methyl-4-phenylpyridinium	Liu et al., 2022
	chemical treatment by environment: N-methyl-4-phenylpyridinium	Christensen et al., 2020
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Díaz-Casado et al., 2017
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Li et al., 2018
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Chen et al., 2022
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Hu et al., 2017
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Yao et al., 2017
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Chen et al., 2020
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Wang et al., 2021
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Soman et al., 2019
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Díaz-Casado et al., 2016
	chemical treatment by environment: N-methyl-4-phenylpyridinium	Duan et al., 2020
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Fueyo-González et al., 2020
	chemical treatment by environment: rotenone	Ünal et al., 2019
	chemical treatment by environment: rotenone	Sürmen et al., 2021
TU	chemical treatment by environment: oxidopamine	Vaz et al., 2019
WT	chemical treatment: oxidopamine	Zhang et al., 2012
	chemical treatment by environment: oxidopamine	Abidar et al., 2020
	chemical treatment by environment: oxidopamine	Feng et al., 2019
	chemical treatment by injection: 6-hydroxy-L-dopa	Vijayanathan et al., 2017
	chemical treatment by injection: oxidopamine	Fiametti et al., 2021
	chemical treatment: N-methyl-4-phenylpyridinium	Pinho et al., 2016
	chemical treatment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Guo et al., 2014
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	de Molliens et al., 2019
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Chen et al., 2017
	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Chen et al., 2017
	chemical treatment by injection: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Bashirzade et al., 2022
	chemical treatment by injection: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Babu et al., 2016
	chemical treatment by environment: oxidopamine	Kesh et al., 2020
	chemical treatment by environment: oxidopamine	Kao et al., 2017
	chemical treatment by environment: rotenone	Shen et al., 2021
	chemical treatment by environment: rotenone	Yurtsever et al., 2020
	chemical treatment by environment: rotenone	Hettiarachchi et al., 2022
	chemical treatment by environment: rotenone	Wang et al., 2017
	chemical treatment by environment: rotenone	Quan et al., 2023
	chemical treatment by environment: rotenone	Lv et al., 2019
atp13a2^nii1/nii1	standard conditions	Nyuzuki et al., 2020
lrrk2^{tud113/tud113}	standard conditions	Suzzi et al., 2021
park7^{ub2000/ub2000}	standard conditions	Edson et al., 2019
pink1^sh397/sh397 (AB)	standard conditions	Soman et al., 2019
pink1^{zf1035/zf1035}	standard conditions	Matsui et al., 2017
slc39a14^u801/u801 (AB)	chemical treatment by environment: manganese(II) chloride	Tuschl et al., 2016
slc45a2^b4/b4	chemical treatment by environment: oxidopamine	Yu et al., 2021
AB + MO1-atp13a2	standard conditions	Lopes da Fonseca et al., 2013
AB + MO1-pink1 + MO2-pink1	standard conditions	Anichtchik et al., 2008
WT + MO1-prkn + MO2-prkn	standard conditions	Flinn et al., 2009
knu3Tg	chemical treatment by environment: oxidopamine	Xi et al., 2022
ot80Tg	chemical treatment: L-dopa	Stednitz et al., 2015
pku2Et	chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	Ren et al., 2022
uio1Tg + CRISPR1-nipsnap1 + CRISPR2-nipsnap1 + CRISPR3-nipsnap1	standard conditions	Princely Abudu et al., 2019
cu49Tg/cu49Tg; s1101tEt/s1101tEt	standard conditions	Lopez et al., 2022
cu50Tg/cu50Tg; cu51Tg/cu51Tg	standard conditions	Lopez et al., 2022
th^{ion32Tg/ion32Tg}; c264Tg/c264Tg	chemical treatment by environment: conduritol B epoxide	Kim et al., 2021
	chemical treatment by environment: metronidazole	Kim et al., 2021

PHENOTYPE No data available

CITATIONS (90)