ZFIN Human Disease: Duchenne muscular dystrophy

OBO ID: DOID:11723

Term Name:	Duchenne muscular dystrophy		Search Ontology:
Synonyms:	Muscular dystrophy, Duchenne
Definition:	A muscular dystrophy that has_material_basis_in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy. (3)
References:	GARD:6291 MESH:D020388 NCI:C75482 OMIM:310200 SNOMEDCT_US_2023_03_01:155095006 UMLS_CUI:C0013264
Ontology:	Human Disease ( DOID:11723 )

Relationships

is a type of:	muscular dystrophy X-linked recessive disease muscular dystrophy X-linked recessive disease Show first 5 Terms

OTHER Duchenne muscular dystrophy PAGES

Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
DMD	dmd	Duchenne muscular dystrophy	310200

ZEBRAFISH MODELS

Fish	Conditions	Citations
dmd^cl100/cl100	standard conditions	(3)
dmd^pc2/pc2	standard conditions	Sztal et al., 2016
dmd^{ta222a/ta222a}	control	Goody et al., 2017
dmd^{ta222a/ta222a}	standard conditions	(2)
dmd^{ta222a/ta222a}	standard conditions	(11)
dmd^{ta222a/ta222a}	electric field	Kilroy et al., 2022
dmd^{ta222a/ta222a} (AB)	standard conditions	English et al., 2022
AB + MO1-dmd + MO6-dmd	standard conditions	Spreafico et al., 2021
WT + MO1-dmd + MO6-dmd	standard conditions	(2)

PHENOTYPE No data available

CITATIONS (22)