OBO ID: DOID:0111036
Term Name: CADASIL 2 Search Ontology:
Synonyms:
  • autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy type 2
Definition: A CADASIL characterized by stroke, transient ischemic attacks, cognitive impairment, dementia, balance impairment, gait disturbance, headaches, and/or seizures associated with early confluent or confluent diffuse white matter hyperintensities that has_material_basis_in heterozygous mutation in the HTRA1 gene on chromosome 10q26. https://www.ncbi.nlm.nih.gov/pubmed/26063658
References:
Ontology: Human Disease   ( DOID:0111036 )
Relationships
is a type of:
inverse disjoint_from:
OTHER CADASIL 2 PAGES
GENES INVOLVED
Human Gene Zebrafish Ortholog OMIM Term OMIM Phenotype ID
HTRA1 Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2 616779
ZEBRAFISH MODELS No data available
PHENOTYPE No data available

CITATIONS: None
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.