ZFIN Human Disease: Holt-Oram syndrome

OBO ID: DOID:0060468

Term Name:	Holt-Oram syndrome		Search Ontology:
Synonyms:	atrio-digital syndrome atriodigital dysplasia heart-hand syndrome
Definition:	A syndrome characterized by congenital anomalies located_in heart and located_in upper limb. (4)
References:	GARD:6666 ICD10CM:Q87.2 MESH:C535326 NCI:C125592 OMIM:142900 ORDO:392 SNOMEDCT_US_2023_03_01:205814003 UMLS_CUI:C0265264
Ontology:	Human Disease ( DOID:0060468 )

Relationships

is a type of:	autosomal dominant disease syndrome autosomal dominant disease syndrome Show first 5 Terms

OTHER Holt-Oram syndrome PAGES

Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
TBX5	tbx5b tbx5a	Holt-Oram syndrome	142900

ZEBRAFISH MODELS

Fish	Conditions	Citations
tbx5a^m21/m21	standard conditions	Garrity et al., 2002
WT + MO1-tbx5a	standard conditions	Garrity et al., 2002
twu34Tg + MO1-tbx5a	standard conditions	Chiavacci et al., 2015
twu34Tg + MO1-tbx5a + MO2-tbx5b	standard conditions	Chiavacci et al., 2015

PHENOTYPE No data available

CITATIONS (4)